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Table 4 Maternal polyunsaturated fatty acids and child neurodevelopment indices from 1 to 30 months of age

From: Polyunsaturated fatty acids and child neurodevelopment among a population exposed to DDT: a cohort study

Polyunsaturated fatty acids

Mental (MDI)

Motor (PDI)

β (95% CI)a

β (95% CI)b

β (95% CI)a

β (95% CI)b

First trimester

 Linoleic (LA) g/day

0.04 (−0.01,0.08)

0.04 (− 0.01,0.09)

0.02 (− 0.04,0.07)

0.02 (− 0.04,0.07)

  Arachidonic (ARA) mg/day

− 0.00 (− 0.01,0.00)

−0.00 (− 0.01,0.00)

−0.00 (− 0.01,0.00)

−0.00 (− 0.01,0.00)

 Alfa linolenic (ALA) g/day

0.62 (0.24,1.00)

0.63 (0.25,1.00)

0.47 (0.01,0.93)

0.46 (0.00,0.93)

  Eicosapentaenoic (EPA) mg/day

0.02 (−0.02,0.06)

0.02 (−0.02,0.06)

− 0.00 (− 0.05,0.04)

−0.00 (− 0.05,0.04)

  Docosapentaenoic (DPA) mg/day

0.10 (0.02,0.18)

0.10 (0.02,0.18)

0.04 (−0.06,0.14)

0.04 (−0.06,0.14)

  Docosahexaenoic (DHA) mg/day

0.01 (−0.01,0.02)

0.01 (−0.01,0.02)

− 0.00 (− 0.02, 0.01)

−0.00 (− 0.02,0.01)

Third trimester

 Linoleic (LA) g/day

0.03 (−0.05,0.11)

0.03 (−0.05,0.11)

− 0.01 (− 0.11,0.09)

−0.01 (− 0.11,0.09)

  Arachidonic (ARA) mg/day

− 0.00 (− 0.01,0.01)

−0.00 (− 0.01,0.01)

0.00 (− 0.01,0.02)

0.00 (− 0.01,0.02)

 Alfa linolenic (ALA) g/day

0.23 (− 0.42,0.89)

0.24 (− 0.42,0.89)

−0.01 (− 0.81,0.78)

−0.02 (− 0.81,0.78)

  Eicosapentaenoic (EPA) mg/day

− 0.01 (− 0.04,0.03)

−0.01 (− 0.04,0.03)

−0.02 (− 0.06,0.02)

−0.02 (− 0.06,0.02)

  Docosapentaenoic (DPA) mg/day

− 0.01 (− 0.09,0.07)

−0.01 (− 0.09,0.07)

−0.04 (− 0.14,0.05)

−0.05 (− 0.14,0.05)

  Docosahexaenoic (DHA) mg/day

− 0.00 (− 0.02,0.01)

−0.00 (− 0.02,0.01)

−0.01 (− 0.02,0.01)

−0.01 (− 0.02,0.01)

  1. aAdjusted by: child’s age at examination (months), Home Observation for Measurement of the Environment scale, gender, maternal intellectual quotient, breastfeeding (months) and energy intake (kilocalories).
  2. bPrevious model plus adjustment by maternal DDE serum levels (ng/g) during the first trimester of pregnancy.
  3. Bold numbers correspond to statistically significant coefficients