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Table 2 Association between maternal urine cotinine in early pregnancy and children’s neurodevelopment at 24 months

From: Exposure to prenatal secondhand smoke and early neurodevelopment: Mothers and Children’s Environmental Health (MOCEH) study

Cotinine

Bayley

n

Mean ± SD

Unadjusteda

Adjustedb

β

95% C.I.

P

β

95% C.I.

P

≤ 1.90

MDI

368

97.05 ± 14.81

1.41

(−1.57, 4.38)

0.35

1.31

(−1.52, 4.14)

0.36

 

PDI

368

96.86 ± 14.07

1.63

(−1.20, 4.46)

0.26

1.88

(−0.90, 4.66)

0.19

> 1.90

MDI

352

96.97 ± 14.24

−1.79

(−4.29, −0.71)

0.16

−2.73

(−5.32, − 0.15)

0.04

 

PDI

352

96.70 ± 12.89

−0.60

(−2.87, 1.67)

0.61

− 0.35

(−2.69, 2.00)

0.77

  1. aGeneral Linear Model adjusted for creatinine
  2. bGeneral Linear Model adjusted for maternal age, maternal education, gestational age, infant sex, region, breastfeeding behavior, primary caregiver, and creatinine
  3. MDI Mental Development Index, PDI Psychomotor Development Index