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Table 2 Association between maternal urine cotinine in early pregnancy and children’s neurodevelopment at 24 months

From: Exposure to prenatal secondhand smoke and early neurodevelopment: Mothers and Children’s Environmental Health (MOCEH) study

Cotinine Bayley n Mean ± SD Unadjusteda Adjustedb
β 95% C.I. P β 95% C.I. P
≤ 1.90 MDI 368 97.05 ± 14.81 1.41 (−1.57, 4.38) 0.35 1.31 (−1.52, 4.14) 0.36
  PDI 368 96.86 ± 14.07 1.63 (−1.20, 4.46) 0.26 1.88 (−0.90, 4.66) 0.19
> 1.90 MDI 352 96.97 ± 14.24 −1.79 (−4.29, −0.71) 0.16 −2.73 (−5.32, − 0.15) 0.04
  PDI 352 96.70 ± 12.89 −0.60 (−2.87, 1.67) 0.61 − 0.35 (−2.69, 2.00) 0.77
  1. aGeneral Linear Model adjusted for creatinine
  2. bGeneral Linear Model adjusted for maternal age, maternal education, gestational age, infant sex, region, breastfeeding behavior, primary caregiver, and creatinine
  3. MDI Mental Development Index, PDI Psychomotor Development Index