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Table 6 Adjusted hazard ratio (95% confidence interval) of self-reported menarche according to urinary fluoride in girlsa

From: Fluoride exposure and pubertal development in children living in Mexico City

 

Specific-gravity adjusted childhood urinary fluoride

N

HR (95% CI)

p-value

Menarche

 Continuous fluoride (mg/L)

175

0.82 (0.51, 1.33)

0.42

 1st tertile (< 0.48)

68

Reference

 2nd tertile (0.49–0.69)

53

0.98 (0.64, 1.51)

0.94

 3rd tertile (0.70–2.61)

55

0.76 (0.50, 1.17)

0.21

  1. HR hazard ratio, CI confidence interval
  2. aAll estimates are from Cox proportional-hazard models adjusted for maternal education and marital status, child BMI z-score and number of siblings at birth