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Table 1 Main characteristics of subjects included in the analysis and cancer subsites

From: Head and neck cancer and occupational exposure to leather dust: results from the ICARE study, a French case-control study

  Cases (n = 2161) Controls (n = 3555) p-value of chi 2 test
n % n %
Age at interview (years, quartiles)      0.003
Mean (SD) 57.8 (8.6) 58.5 (10.2)  
 <  51 467 21.6 899 25.3  
 51–60 767 35.5 812 22.8  
 59–65 508 23.5 801 22.5  
 ≥66 419 19.4 1043 29.3  
Sex      <  0.0001
 Male 1862 86.2 2780 78.2  
 Female 299 13.8 775 21.8  
Area of residence      <  0.0001
 Bas-Rhin 232 10.7 469 13.2  
 Calvados 210 9.7 462 13.0  
 Doubs, Territoire de Belfort 47 2.2 143 4.0  
 Hérault 227 10.5 450 12.7  
 Isère 250 11.6 501 14.1  
 Loire Atlantique 359 16.6 404 11.4  
 Manche 238 11.0 312 8.8  
 Haut-Rhin 39 1.8 118 3.3  
 Somme 394 18.3 499 14.0  
 Vendée 165 7.6 197 5.5  
Socioeconomic status (the longest held job)      <  0.0001
 Managers 134 6.2 618 17.4  
 Farmers 51 2.4 197 5.5  
 Self-employed workers 136 6.3 177 4.9  
 Intermediate white-collar workers 218 10.1 695 19.5  
 Office and sales employees 341 15.8 672 18.9  
 Blue-collar workers 1241 57.4 1178 33.1  
Tobacco smoking status      <  0.0001
 Never smokers 110 5.1 1262 35.5  
 Former smokers a 589 27.3 1461 40.1  
 Current smokers 1452 67.2 820 23.1  
Tobacco-smoking (pack-years, quartiles)      <  0.0001
 Mean (SD) 38.3 (25.2) 13.2 (18.4)  
 Never smokers 110 5.1 1262 35.5  
 <  7 94 4.3 581 16.6  
 7–16 174 8.1 566 16.1  
 17–29 376 17.4 535 15.2  
 >  29 1361 62.9 566 16.1  
Alcohol drinking (glass-years, quartiles)     <  0.0001
 Mean (SD) 213.1 (233.6) 78.3 (120.1)  
 Never drinkers 103 4.8 306 8.6  
 <  9 149 6.9 803 22.6  
 9–46 174 8.1 806 22.7  
 47–118 378 17.5 804 22.6  
 >  118 1273 58.9 802 22.6  
Cancer subsitesb
 Oral cavity 444 20.5  
 Oropharynx 658 30.5  
 Hypopharynx 405 18.7  
 Oral cavity/pharynx unspecified 148 6.8  
 Larynx 506 23.5  
  1. a Former smokers were subjects who had stopped smoking at least two years before the interview (controls) or diagnosis (cases)
  2. b Only squamous cell carcinomas were included in the study