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Table 3 Associations between the risk of head and neck cancer and materials handled, tasks performed, and glues used. Results from the specific questionnaire on leather work

From: Head and neck cancer and occupational exposure to leather dust: results from the ICARE study, a French case-control study

 

Cases (n = 1926)

Controls (n = 3481)

ORa (95% CI)

n

%

n

%

Held at least one job exposed to leather dust and filled out at least one specific questionnaire

 No b

1902

98.8

3450

99.1

reference

 Yes

24

1.2

31

0.9

1.15 (0.57, 2.31)

Materials handled

 Exposure to soft leather

  Never

2

0.1

5

0.1

0.95 (0.16, 5.63)

  Ever

19

0.9

24

0.6

1.33 (0.61, 2.92)

 Exposure to thick leather

  Never

7

0.3

9

0.2

1.86 (0.55, 6.25)

 Ever

14

0.7

21

0.6

0.86 (0.36, 2.06)

 Exposure to crepe rubber

  Never

9

0.4

21

0.6

0.77 (0.28, 2.05)

  Ever

10

0.5

7

0.2

1.93 (0.57, 6.54)

 Exposure to synthetic leather

  Never

12

0.6

14

0.4

1.14 (0.41, 3.14)

  Ever

10

0.5

15

0.4

1.44 (0.53, 3.86)

 Exposure to textile materials

     

  Never

17

0.8

18

0.5

1.69 (0.70, 4.03)

  Ever

6

0.3

11

0.3

0.75 (0.21, 2.56)

 Exposure to other materials c

  Never

15

0.7

25

0.7

0.88 (0.39, 2.01)

  Ever

7

0.3

1

< 0.1

18.75 (1.77, 197.89)

Tasks performed

 Cutting of leather

  Never

5

0.2

9

0.2

1.08 (0.25, 4.51)

  Ever

18

0.9

21

0.6

1.17 (0.52, 2.63)

 Cutting of other materials

  Never

10

0.5

14

0.4

1.61 (0.53, 4.88)

  Ever

12

0.6

16

0.4

1.03 (0.41, 2.57)

 Scouring, roughing, grinding, trimming, buffing of leather

  Never

9

0.4

15

0.4

1.14 (0.39, 3.30)

  Ever

13

0.6

14

0.4

1.49 (0.56, 3.92)

 Gluing

  Never

6

0.3

8

0.2

2.88 (0.74, 11.2)

  Ever

18

0.9

22

0.6

1.02 (0.47, 2.23)

 Sewing

  Never

7

0.3

8

0.2

0.80 (0.22, 2.85)

  Ever

17

0.8

23

0.6

1.34 (0.59, 3.05)

 Dyeing

  Never

14

0.7

24

0.6

0.81 (0.34, 1.91)

  Ever

9

0.4

6

0.1

3.22 (0.77, 13.32)

 Injection of plastic materials

  Never

19

0.9

26

0.7

1.39 (0.64, 3.02)

  Ever

3

0.1

3

< 0.1

0.84 (0.12, 5.95)

 Other tasks d

  Never

19

 

24

 

1.17 (0.54, 2.51)

  Ever

2

0.1

2

0.1

8.08 (0.66, 98.21)

Glues used

 Neoprene glues

  Never

6

0.3

7

0.2

0.55 (0.14, 2.05)

  Ever

18

0.9

24

0.6

1.52 (0.68, 3.39)

 Solvent-based / rubber-based adhesives

  Never

6

0.3

7

0.2

1.03 (0.27, 3.92)

  Ever

18

0.9

24

0.6

1.20 (0.53, 2.71)

 Strong glues/animal skin glues

  Never

6

0.3

10

0.2

0.54 (0.15, 1.94)

  Ever

18

0.9

21

0.6

1.60 (0.70, 3.65)

 Polyurethane glues

  Never

10

0.5

7

0.2

1.87 (0.54, 6.49)

  Ever

14

0.7

24

0.6

0.92 (0.39, 2.16)

 Other glues

  Never

6

0.3

9

0.2

0.99 (0.28, 3.43)

  Ever

17

0.8

22

0.6

1.21 (0.52, 2.82)

  1. a ORs (odds ratios) adjusted for age, sex, area of residence, socioeconomic status, and tobacco and alcohol consumption
  2. b Reference category for all analyses on materials handled, tasks performed, and glues used was the category of subjects that never held a job entailing leather dust exposure and that did not filled out (a) specific leather questionnaire(s)
  3. c Wood, cork, cardboard, twine, pitch
  4. d Shoes varnishing, polishing and brushing