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Table 4 Models results for the interaction between para-occupational pesticide exposure during pregnancy and PON1 genotypes on maternal hypoythyroxinemia
| Maternal PON 1 Genotype | Para-occupational exposure during pregnancy | |||||
|---|---|---|---|---|---|---|
| Yes | No | |||||
| n | Crude OR (95% CI) | Adjusted ORa (95% CI) | n | Crude OR (95% CI) | Adjusted ORa (95% CI) | |
| PON1192 | ||||||
| 55 | 1.10 (0.52–2.34) | 0.97 (0.44–2.15) | 64 | 1.0 | 1.0 | |
| QR | 66 | 1.27 (0.47–3.43) | 1.28 (0.45–3.62) | 95 | 0.81 (0.42–1.56) | 0.78 (0.75–1.94) |
| RR | 41 | 1.61 (0.50–5.14) | 1.52 (0.46–5.04) | 60 | 1.41 (0.67–2.96) | 1.39 (0.64–3.0) |
| p for interaction: 0.78 | ||||||
| PON155 | ||||||
| LL | 82 | 1.13 (0.63–2.04) | 1.07 (0.58–1.99) | 113 | 1.0 | 0.94–1.091.0 |
| LM | 45 | 1.31 (0.48–3.56) | 1.15 (0.41–3.25) | 58 | 0.84 (0.44–1.62) | 1.02 (0.51–2.05) |
| MM | 35 | 1.87 (0.55–6.38) | 1.49 (0.42–5.27) | 48 | 1.96 (0.94–4.09) | 2.59 (1.21–5.57) |
| p for interaction: 0.82 | ||||||
| PON1108 | ||||||
| CC | 54 | 0.85 (0.41–1.76) | 0.70 (0.32–1.49) | 76 | 1 | 1.0 |
| CT | 62 | 1.98 (0.72–5.48) | 2.11 (0.73–6.10) | 78 | 1.00 (0.52–1.95) | 0.98 (0.48–1.49) |
| TT | 46 | 2.11 (0.71–6.33) | 2.49 (0.79–7.81) | 65 | 1.02 (0.51–2.04) | 0.96 (0.47–1.98) |
| p for interaction: 0.23 | ||||||
