|
Maternal PON 1 Genotype
| |
Para-occupational exposure during pregnancy
|
|---|
|
Yes
|
No
|
|---|
|
n
|
Crude OR (95% CI)
|
Adjusted ORa (95% CI)
|
n
|
Crude OR (95% CI)
|
Adjusted ORa (95% CI)
|
|---|
|
PON1192
|
|
QQ
|
55
|
1.10 (0.52–2.34)
|
0.97 (0.44–2.15)
|
64
|
1.0
|
1.0
|
|
QR
|
66
|
1.27 (0.47–3.43)
|
1.28 (0.45–3.62)
|
95
|
0.81 (0.42–1.56)
|
0.78 (0.75–1.94)
|
|
RR
|
41
|
1.61 (0.50–5.14)
|
1.52 (0.46–5.04)
|
60
|
1.41 (0.67–2.96)
|
1.39 (0.64–3.0)
|
|
p for interaction: 0.78
|
|
PON155
|
|
LL
|
82
|
1.13 (0.63–2.04)
|
1.07 (0.58–1.99)
|
113
|
1.0
|
0.94–1.091.0
|
|
LM
|
45
|
1.31 (0.48–3.56)
|
1.15 (0.41–3.25)
|
58
|
0.84 (0.44–1.62)
|
1.02 (0.51–2.05)
|
|
MM
|
35
|
1.87 (0.55–6.38)
|
1.49 (0.42–5.27)
|
48
|
1.96 (0.94–4.09)
|
2.59 (1.21–5.57)
|
|
p for interaction: 0.82
|
|
PON1108
|
|
CC
|
54
|
0.85 (0.41–1.76)
|
0.70 (0.32–1.49)
|
76
|
1
|
1.0
|
|
CT
|
62
|
1.98 (0.72–5.48)
|
2.11 (0.73–6.10)
|
78
|
1.00 (0.52–1.95)
|
0.98 (0.48–1.49)
|
|
TT
|
46
|
2.11 (0.71–6.33)
|
2.49 (0.79–7.81)
|
65
|
1.02 (0.51–2.04)
|
0.96 (0.47–1.98)
|
|
p for interaction: 0.23
|
- aModels were adjusted by: maternal age, gestational age, maternal education, coffee intake, and body mass index
