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Table 4 Models results for the interaction between para-occupational pesticide exposure during pregnancy and PON1 genotypes on maternal hypoythyroxinemia

From: Para-occupational exposure to pesticides, PON1 polymorphisms and hypothyroxinemia during the first half of pregnancy in women living in a Mexican floricultural area

Maternal PON 1 Genotype   Para-occupational exposure during pregnancy
Yes No
n Crude OR (95% CI) Adjusted ORa (95% CI) n Crude OR (95% CI) Adjusted ORa (95% CI)
PON1192
 QQ 55 1.10 (0.52–2.34) 0.97 (0.44–2.15) 64 1.0 1.0
 QR 66 1.27 (0.47–3.43) 1.28 (0.45–3.62) 95 0.81 (0.42–1.56) 0.78 (0.75–1.94)
 RR 41 1.61 (0.50–5.14) 1.52 (0.46–5.04) 60 1.41 (0.67–2.96) 1.39 (0.64–3.0)
p for interaction: 0.78
PON155
 LL 82 1.13 (0.63–2.04) 1.07 (0.58–1.99) 113 1.0 0.94–1.091.0
 LM 45 1.31 (0.48–3.56) 1.15 (0.41–3.25) 58 0.84 (0.44–1.62) 1.02 (0.51–2.05)
 MM 35 1.87 (0.55–6.38) 1.49 (0.42–5.27) 48 1.96 (0.94–4.09) 2.59 (1.21–5.57)
p for interaction: 0.82
PON1108
 CC 54 0.85 (0.41–1.76) 0.70 (0.32–1.49) 76 1 1.0
 CT 62 1.98 (0.72–5.48) 2.11 (0.73–6.10) 78 1.00 (0.52–1.95) 0.98 (0.48–1.49)
 TT 46 2.11 (0.71–6.33) 2.49 (0.79–7.81) 65 1.02 (0.51–2.04) 0.96 (0.47–1.98)
p for interaction: 0.23
  1. aModels were adjusted by: maternal age, gestational age, maternal education, coffee intake, and body mass index