Genotype
|
Control
|
NIHL
|
P-valuea
|
OR (95% CI)a
|
---|
Pcdh15/rs11004085
|
TT
|
346
|
382
|
0.015
|
1
|
CT
|
120
|
88
|
0.005
|
0.59 (0.41, 0.85)
|
CC
|
5
|
3
|
0.395
|
0.53 (0.12, 2.31)
|
Ptrend
| | |
0.005
| |
CT/CC
|
125
|
91
|
0.004
|
0.59 (0.41, 0.84)
|
EYA4/ rs3777781
|
TT
|
137
|
166
|
0.045
|
1
|
AT
|
236
|
235
|
0.116
|
0.76 (0.54, 1.07)
|
AA
|
96
|
71
|
0.015
|
0.57 (0.36, 0.90)
|
Ptrend
| | |
0.016
| |
AT/AA
|
332
|
306
|
0.047
|
0.72 (0.52, 0.99)
|
EYA4/ rs212769
|
GG
|
354
|
336
|
0.094
|
1
|
AG
|
112
|
129
|
0.062
|
1.40 (0.98, 1.98)
|
AA
|
5
|
8
|
0.214
|
2.37 (0.61, 9.23)
|
Ptrend
| | |
0.033
| |
AG/AA
|
117
|
137
|
0.041
|
1.43 (1.01, 2.02)
|
MYO1A/rs1552245
|
GG
|
293
|
308
|
0.088
|
1
|
AG
|
164
|
156
|
0.032
|
0.70 (0.51, 0.97)
|
AA
|
14
|
8
|
0.448
|
0.68 (0.25, 1.84)
|
Ptrend
| | |
0.032
| |
AG/AA
|
178
|
164
|
0.027
|
0.70 (0.51, 0.96)
|
DFNA5/ rs2521768
|
TT
|
289
|
305
|
0.158
|
1
|
CT
|
155
|
148
|
0.249
|
0.82 (0.60, 1.14)
|
CC
|
27
|
19
|
0.089
|
0.52 (0.25, 1.10)
|
Ptrend
| | |
0.064
| |
CT/CC
|
182
|
167
|
0.122
|
0.78 (0.57, 1.07)
|
CDH23/rs2394795
|
CC
|
134
|
108
|
0.122
|
1
|
TC
|
240
|
244
|
0.081
|
1.39 (0.96, 2.02)
|
TT
|
97
|
120
|
0.06
|
1.53 (0.98, 2.38)
|
Ptrend
| | |
0.058
| |
TC/TT
|
337
|
364
|
0.043
|
1.44 (1.01, 2.05)
|
CDH23/rs4747192
|
CC
|
168
|
193
|
0.213
|
1
|
TC
|
230
|
220
|
0.113
|
0.77 (0.55, 1.06)
|
TT
|
73
|
60
|
0.189
|
0.73 (0.45, 1.17)
|
Ptrend
| | |
0.106
| |
TC/TT
|
303
|
280
|
0.084
|
0.76 (0.56, 1.04)
|
MYO7A/ rs1043421
|
TT
|
252
|
282
|
0.16
|
1
|
AT
|
192
|
170
|
0.066
|
0.74 (0.54, 1.02)
|
AA
|
28
|
21
|
0.384
|
0.73 (0.37, 1.47)
|
Ptrend
| | |
0.071
| |
AT/AA
|
220
|
191
|
0.057
|
0.74 (0.55, 1.01)
|
KCNMA1/rs696211
|
TT
|
247
|
247
|
0.052
|
1
|
CT
|
178
|
194
|
0.904
|
0.98 (0.71, 1.35)
|
CC
|
45
|
31
|
0.016
|
0.47 (0.26, 0.87)
|
Ptrend
| | |
0.080
| |
TT + CT
|
425
|
441
|
0.016
|
0.48 (0.26, 0.87)
|
KCNMA1/ rs7910544
|
GG
|
343
|
345
|
0.175
|
1
|
CG
|
121
|
111
|
0.652
|
0.92(0.65, 1.31)
|
CC
|
7
|
16
|
0.077
|
2.70(0.90, 8.11)
|
Ptrend
| | |
0.576
| |
GG + CG
|
7
|
16
|
0.070
|
2.76(0.92,8.26)
|
CX43/rs3751385
|
CC
|
131
|
109
|
0.134
|
1
|
CT
|
259
|
265
|
0.071
|
1.40 (0.97, 2.01)
|
TT
|
80
|
99
|
0.086
|
1.50 (0.94, 2.39)
|
Ptrend
| | |
0.081
| |
CT/TT
|
339
|
364
|
0.056
|
1.41 (0.99, 1.99)
|
GRHL2/ rs471757
|
CC
|
158
|
167
|
0.161
|
1
|
CT
|
208
|
217
|
0.889
|
0.98 (0.69, 1.37)
|
TT
|
105
|
89
|
0.078
|
0.68 (0.45, 1.04)
|
Ptrend
| | |
0.104
| |
CC + CT
|
366
|
384
|
0.062
|
0.70 (0.48, 1.02)
|
GRHL2/ rs666026
|
TT
|
244
|
222
|
0.147
|
1
|
GT
|
186
|
204
|
0.118
|
1.29 (0.94, 1.77)
|
GG
|
40
|
46
|
0.121
|
1.55 (0.89, 2.71)
|
Ptrend
| | |
0.051
| |
GT/GG
|
226
|
250
|
0.065
|
1.33 (0.98, 1.80)
|
OTOG/ rs7106021
|
GG
|
340
|
326
|
0.031
|
1
|
GA
|
116
|
136
|
0.014
|
1.55(1.09, 2.20)
|
AA
|
14
|
10
|
0.485
|
0.72(0.29, 1.81)
|
Ptrend
| | |
0.123
| |
GA + AA
|
130
|
146
|
0.036
|
1.43(1.02, 2.00)
|
- a calculated with logistic regression adjusted by age, CNE, smoking, and drinking