Table 2 Associations between levels of GRS and risk for NIHL
GRS | Control | Case | Total | P-value | OR(95% CI) |
|---|---|---|---|---|---|
Median (P25, P75) | 8.0 (7.0, 9.0) | 9.0 (7.0, 10.0) | 8.0 (7.0, 9.0) | < 0.001 | |
GRS subgroup, n (%) | |||||
< 7 | 84 (17.9) | 46 (9.7) | 130 (13.8) | 1 | |
7 | 80 (17.1) | 78 (16.5) | 158 (16.8) | 0.005 | 2.04 (1.24, 3.38) |
8 | 120 (25.6) | 109 (23.1) | 229 (24.3) | 0.01 | 1.85 (1.16, 2.96) |
9 | 105 (22.4) | 102 (21.6) | 207 (22.0) | 0.005 | 1.98 (1.23, 3.20) |
10 | 47 (10.0) | 69 (14.6) | 116 (12.3) | < 0.001 | 3.22 (1.86, 5.57) |
≥11 | 33 (7.0) | 68 (14.4) | 101 (10.7) | < 0.001 | 5.13 (2.87, 9.16) |
P trend | < 0.001 | ||||
< 9 | 284 (60.6) | 233 (49.4) | 517 (54.9) | 1 | |
≥9 | 185 (39.4) | 239 (50.6) | 424 (45.1) | 0.001 | 1.58 (1.22, 2.04) |