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Fig. 4 | Environmental Health

Fig. 4

From: Two-step approach for assessing the health effects of environmental chemical mixtures: application to simulated datasets and real data from the Navajo Birth Cohort Study

Fig. 4

Analysis of Local Simulated Dataset (With Interaction). The forest plot describing the regression coefficients (boxes) and their 95% confidence intervals (lines) for modeling the relationship between exposure variables and outcome using three methods: (a) single step adaptive lasso (green); (b) two-step with CART followed by adaptive lasso approach (blue); and (c) two-step with RF followed by adaptive lasso approach (red). The black boxes indicate the true parameter coefficients (\( \widehat{\beta} \)) used in the simulation. True nonzero covariates were set to include: main effects of X1, X2, X9, X12, X15, X16, and interaction effects between X1 and X12. The numbers on X axis represent the magnitude of the regression coefficients

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