|
OC concentrations
|
Model 1
|
Model 2
|
|---|
|
β
|
SE
|
P-value
|
β
|
SE
|
P-value
|
|---|
|
PCB congeners
|
|
PCB 105
|
−0.811
|
0.509
|
0.111
|
−0.780
|
0.544
|
0.151
|
|
PCB 118
|
−1.225
|
0.581
|
0.035
|
−1.207
|
0.611
|
0.048
|
|
PCB 138
|
−1.219
|
0.626
|
0.052
|
−1.223
|
0.644
|
0.058
|
|
PCB 153
|
−1.387
|
0.705
|
0.049
|
− 1.449
|
0.727
|
0.046
|
|
PCB 156
|
−1.509
|
0.755
|
0.046
|
−1.586
|
0.780
|
0.042
|
|
PCB 163
|
−1.501
|
0.699
|
0.032
|
−1.602
|
0.724
|
0.027
|
|
PCB 170
|
−0.830
|
0.691
|
0.230
|
−0.908
|
0.708
|
0.200
|
|
PCB 180
|
−0.521
|
0.688
|
0.448
|
−0.611
|
0.707
|
0.390
|
|
PCB 183
|
−0.948
|
0.611
|
0.121
|
−0.968
|
0.629
|
0.124
|
|
PCB 187
|
−0.149
|
0.580
|
0.797
|
−0.215
|
0.601
|
0.721
|
|
OC pesticides
|
|
β-HCH
|
−0.751
|
0.590
|
0.203
|
−0.699
|
0.606
|
0.249
|
|
HCB
|
−0.737
|
0.519
|
0.156
|
−0.644
|
0.541
|
0.233
|
|
Oxychlordane
|
−0.602
|
0.803
|
0.454
|
−0.540
|
0.824
|
0.512
|
|
cis-nonachlor
|
−0.044
|
0.585
|
0.940
|
+ 0.038
|
0.627
|
0.952
|
|
trans-Nonachlor
|
−0.351
|
0.714
|
0.623
|
−0.332
|
0.742
|
0.655
|
|
p,p’-DDT
|
−1.717
|
0.468
|
< 0.001
|
−1.693
|
0.487
|
< 0.001
|
|
p,p’-DDE
|
−1.554
|
0.414
|
< 0.001
|
−1.578
|
0.422
|
< 0.001
|
- Note: 3MS Modified Mini-Mental State Examination, β beta, BMI body mass index, β-HCH beta hexachlorocyclohexane, HCB hexaclorobenzene, OC organochlorine, PCBs polychlorinated biphenyls, p,p’-DDT, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane; p,p’-DDE, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene, SE standard error
- Repeated measures regression models with unstructured correlation matrix
- Model 1 was adjusted for total lipids and CSHA phase, age, sex, education, and ApoE4
- Model 2 was additionally adjusted for BMI, smoking, alcohol drinking, residence area, vascular score, copper, lead, mercury and zinc
