|
Aimed event
|
Smoking status
|
Direct effect1
|
Indirect effect1
|
Total effect1
|
PM2
|
|---|
|
estimate
|
95% CI3
|
estimate
|
95% CI3
|
estimate
|
95% CI3
|
|---|
|
Acute coronary event
|
Never smoker
| | | | | | | |
|
Long time former smoker
|
1.00
|
0.85, 1.19
|
1.00
|
0.99, 1.00
|
1.00
|
0.85, 1.19
| |
|
Recent former smoker
|
0.83
|
0.64, 1.09
|
0.99
|
0.96, 1.02
|
0.83
|
0.63, 1.08
|
5%
|
|
Current smoker
|
0.75a
|
0.60, 0.94
|
0.96
|
0.84, 1.09
|
0.72a
|
0.60, 0.86
|
12%
|
|
Major adverse coronary event
|
Never smoker
| | | | | | | |
|
Long time former smoker
|
0.93
|
0.79, 1.09
|
1.00
|
0.99, 1.00
|
0.92
|
0.79, 1.08
| |
|
Recent former smoker
|
0.85
|
0.66, 1.10
|
0.96a
|
0.93, 0.99
|
0.82
|
0.63, 1.06
|
21%
|
|
Current smoker
|
0.86
|
0.70, 1.07
|
0.85a
|
0.75, 0.96
|
0.73a
|
0.62, 0.87
|
48%
|
|
Stroke
|
Never smoker
| | | | | | | |
|
Long time former smoker
|
1.17
|
0.95, 1.43
|
1.00
|
0.99, 1.00
|
1.16
|
0.95, 1.43
| |
|
Recent former smoker
|
0.89
|
0.65, 1.21
|
0.98
|
0.94, 1.02
|
0.87
|
0.64, 1.18
|
15%
|
|
Current smoker
|
0.81
|
0.63, 1.06
|
0.93
|
0.79, 1.08
|
0.75a
|
0.61, 0.92
|
25%
|
|
Cardiovascular mortality
|
Never smoker
| | | | | | | |
|
Long time former smoker
|
0.98
|
0.94, 1.02
|
1.00
|
1.00, 1.00
|
0.98
|
0.94, 1.02
| |
|
Recent former smoker
|
0.97
|
0.9, 1.05
|
1.00
|
0.99, 1.00
|
0.97
|
0.90, 1.04
|
0%
|
|
Current smoker
|
0.90a
|
0.85, 0.95
|
0.99
|
0.95, 1.02
|
0.89a
|
0.85, 0.93
|
8%
|
|
All-cause mortality
|
Never smoker
| | | | | | | |
|
Long time former smoker
|
0.98
|
0.95, 1.01
|
1.00
|
1.00, 1.00
|
0.98
|
0.95, 1.00
| |
|
Recent former smoker
|
0.95
|
0.91, 1.00
|
0.99
|
0.99, 1.00
|
0.95a
|
0.91, 0.99
|
20%
|
|
Current smoker
|
0.88a
|
0.85, 0.91
|
0.97a
|
0.96, 0.99
|
0.86a
|
0.84, 0.88
|
20%
|
- 1The effects are presented as fold change of survival time; 2PM: proportion mediated (presented for recent former smokers and current smokers); 395% CI: 95% confidence interval; 4) adenotes P < 0.05
