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Table 6 Linear mixed effect model testing SES and biomarkers interaction term association with neurocognitive outcomes

From: Neurocognitive impact of metal exposure and social stressors among schoolchildren in Taranto, Italy

  SES Mid vs Low SES High vs Low log(BPb) SES Mid vs Low X log(BPb) SES High vs Low X log(BPb)
IQ 1.0 (−2.8, 4.9) 5.2a (0.3, 10.4) −2.7 (−5.6, 0.2) 2.2 (− 1.7, 5.8) 1.8 (− 2.8, 6.4)
GAI 1.1 (− 2.9, 5.6) 6.3a (1.0, 11.8) − 3.5a (− 6.7, − 0.3) 2.8 (− 1.1, 7.3) 2.5 (− 2.0, 7.3)
CPI 0.3 (− 3.6, 4.3) 2.0 (− 2.9, 7.1) −3.5a (− 6.7, − 0.7) 4.1a (0.2, 7.9) 1.6 (−2.9, 6.0)
WMI 0.9 (− 3.0, 4.9) 6.1a (1.3, 11.0) − 4.0a (− 6.9, − 1.1) 4.5a (0.8, 8.3) 4.9a (0.4, 9.4)
PSI 2.0 (−2.0, 5.9) − 0.5 (− 5.9, 4.1) − 0.8 (− 3.9, 2.3) 1.5 (− 2.8, 5.3) 0.6 (−3.6, 5.2)
PRI 0.01 (− 4.0, 3.7) 2.1 (− 2.8, 7.4) − 1.3 (− 4.3, 1.8) 0.4 (− 3.4, 4.2) 2.2 (−2.3, 7.0)
VCI 2.4 (−1.8, 6.7) 8.2a (1.9, 14.4) −2.2 (− 5.3, 0.9) − 0.2 (− 4.3, 4.0) 2.7 (− 2.5, 7.9)
  1. Notes: Linear mixed effect model β coefficients and 95% confidence intervals (CI) for SES, BPb concentration and the interaction term between SES and BPb for the association with IQ and its sub-scores. All the models were adjusted for age, sex, maternal SPM, HOME total score, and distance from the point source
  2. SES Socio-economic status, BPb blood lead, IQ Intellectual Quotient, VCI Verbal Comprehension Index, PRI Visual-Perceptual Reasoning Index, WMI Working Memory Index, PSI Processing Speed Index, GAI General Ability Index, CPI Cognitive Proficiency Index
  3. aStatistically significant difference from 0