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Fig. 1 | Environmental Health

Fig. 1

From: CYP1A1 methylation mediates the effect of smoking and occupational polycyclic aromatic hydrocarbons co-exposure on oxidative DNA damage among Chinese coke-oven workers

Fig. 1

Co-exposure effects of smoking and urine PAH metabolites on risk of CYP1A1 hypomethylation and high 8-OHdG. The statuses of smoking were stratified by non-smokers and smokers. The levels of urine PAH metabolites were stratified by the highest tertile into low exposure (< 67th percentile) and high exposure (≥ 67th percentile). The levels of CYP1A1 methylation were stratified by the median (3.03) into CYP1A1 hypomethylation (< 3.03) and CYP1A1 hypermethylation (≥ 3.03). The levels of urine 8-OHdG were stratified by the median (204.05 mmol/mol Cr) into low 8-OHdG (< 204.05 mmol/mol Cr) and high 8-OHdG (≥ 204.05 mmol/mol Cr). Adjusted for sex, age, years of working, drinking status, education and central heating

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Environmental Health

ISSN: 1476-069X