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Table 1 Essential information and laboratory parameters among 500 occupational workers

From: CYP1A1 methylation mediates the effect of smoking and occupational polycyclic aromatic hydrocarbons co-exposure on oxidative DNA damage among Chinese coke-oven workers

Variables alow 8-OHdG (≤ 204.05 mmol/mol Cr)high 8-OHdG (>  204.05 mmol/mol Cr)P b
Sex
 Male217 (86.8)228 (91.2)0.116
 Female33 (13.2)22 (8.8) 
Age (years)39 (32–45)41 (37–46)0.009
Years of working20 (14–27)22 (17–28)0.007
Education (years)
  < 953 (21.1)66 (26.4)0.273
 9–1292 (36.8)94 (37.6) 
  > 12105 (42.0)90 (36.0) 
Occupation
 Coke oven worker191 (76.4)198 (79.2)0.451
 Water treatment worker59 (23.6)52 (20..8) 
Central heating
 yes237 (94.8)233 (93.2)0.451
 no13 (5.2)17 (6.8) 
Smoking status
 yes94 (37.9)132 (53.2)0.001
 no154 (62.1)116 (46.8) 
Drinking status
 yes142 (56.8)178 (71.2)0.001
 no108 (43.2)72 (28.8) 
1-OHP (μg/mmol Cr)0.05 (0.03–0.09)0.06 (0.04–0.10)0.144
2-NAP (μg/mmol Cr)0.65 (0.36–1.07)0.79 (0.44–1.25)0.007
2-FLU (μg/mmol Cr)0.26 (0.17–0.46)0.28 (0.19–0.43)0.395
9-PHE (μg/mmol Cr)0.08 (0.06–0.14)0.09 (0.06–0.17)0.856
ΣPAH (μg/mmol Cr)0.27 (0.18–0.46)0.34 (0.23–0.48)0.014
CYP1A1 methylation
 pos.12.95 (0.00–4.36)2.43 (0.00–4.07)0.129
 pos.22.19 (0.00–3.47)1.83 (0.00–3.49)0.913
 pos.34.83 (2.24–6.17)3.92 (0.00–6.00)0.055
 pos.42.40 (0.00–3.94)2.09 (0.00–3.51)0.477
 pos.52.52 (0.00–4.53)1.43 (0.00–3.99)0.060
 average3.10 (1.63–4.20)2.42 (1.29–3.85)0.031
  1. Drinking status missing 4 values
  2. a Data were presented as n (%) or Median (25th - 75th)
  3. b P-values were calculated from Chi-square test for categorical variables and Mann-Whitney U test for numerical variables