Table 1 Essential information and laboratory parameters among 500 occupational workers
Variables a | low 8-OHdG (≤ 204.05 mmol/mol Cr) | high 8-OHdG (>  204.05 mmol/mol Cr) | P b |
|---|---|---|---|
Sex | |||
 Male | 217 (86.8) | 228 (91.2) | 0.116 |
 Female | 33 (13.2) | 22 (8.8) |  |
Age (years) | 39 (32–45) | 41 (37–46) | 0.009 |
Years of working | 20 (14–27) | 22 (17–28) | 0.007 |
Education (years) | |||
  < 9 | 53 (21.1) | 66 (26.4) | 0.273 |
 9–12 | 92 (36.8) | 94 (37.6) |  |
  > 12 | 105 (42.0) | 90 (36.0) |  |
Occupation | |||
 Coke oven worker | 191 (76.4) | 198 (79.2) | 0.451 |
 Water treatment worker | 59 (23.6) | 52 (20..8) |  |
Central heating | |||
 yes | 237 (94.8) | 233 (93.2) | 0.451 |
 no | 13 (5.2) | 17 (6.8) |  |
Smoking status | |||
 yes | 94 (37.9) | 132 (53.2) | 0.001 |
 no | 154 (62.1) | 116 (46.8) |  |
Drinking status | |||
 yes | 142 (56.8) | 178 (71.2) | 0.001 |
 no | 108 (43.2) | 72 (28.8) |  |
1-OHP (μg/mmol Cr) | 0.05 (0.03–0.09) | 0.06 (0.04–0.10) | 0.144 |
2-NAP (μg/mmol Cr) | 0.65 (0.36–1.07) | 0.79 (0.44–1.25) | 0.007 |
2-FLU (μg/mmol Cr) | 0.26 (0.17–0.46) | 0.28 (0.19–0.43) | 0.395 |
9-PHE (μg/mmol Cr) | 0.08 (0.06–0.14) | 0.09 (0.06–0.17) | 0.856 |
ΣPAH (μg/mmol Cr) | 0.27 (0.18–0.46) | 0.34 (0.23–0.48) | 0.014 |
CYP1A1 methylation | |||
 pos.1 | 2.95 (0.00–4.36) | 2.43 (0.00–4.07) | 0.129 |
 pos.2 | 2.19 (0.00–3.47) | 1.83 (0.00–3.49) | 0.913 |
 pos.3 | 4.83 (2.24–6.17) | 3.92 (0.00–6.00) | 0.055 |
 pos.4 | 2.40 (0.00–3.94) | 2.09 (0.00–3.51) | 0.477 |
 pos.5 | 2.52 (0.00–4.53) | 1.43 (0.00–3.99) | 0.060 |
 average | 3.10 (1.63–4.20) | 2.42 (1.29–3.85) | 0.031 |