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Table 3 Regression coefficients from the association of PBB exposure and thyroid hormone levels in total study population

From: Thyroid hormone levels associate with exposure to polychlorinated biphenyls and polybrominated biphenyls in adults exposed as children

  Total T4 (μ g/dL) Total T3 (ng/mL) Free T4 (ng/dL) Free T3 (pg/mL) TSH (μ IU/mL) Free T3: Free T4 ratio
Model Variables β (95% CI) β (95% CI) β (95% CI) β (95% CI) β (95% CI) β (95% CI)
1 Total PBB (ppb) 0.0048 (− 0.0041, 0.0139) 0.0079 (− 0.0025, 0.0184) − 0.0116(− 0.0202, − 0.0030) 0.0104 (0.0036, 0.0172) 0.0218 (− 0.0110,0.0547) 0.0840 (0.0418, 0.1262)
Current Age (years) − 0.0006 (− 0.0013, 0.0012) −0.0056 (− 0.0071, − 0.0042) 0.0005 (− 0.0006, 0.0017) − 0.0028 (− 0.0038, − 0.0019) 0.0032 (− 0.0013,0.0078) −0.0141 (− 0.0200, − 0.0082)
Sex −0.0449 (− 0.0763, − 0.0136) −0.0154 (− 0.0515, 0.0212) −0.0004 (− 0.0304, 0.0294) 0.0414 (0.0178, 0.0651) 0.0311 (− 0.0830, 0.1452) 0.1555 (0.0091, 0.3020)
Lipids (mg/dL) −0.00008 (− 0.0001, − 0.00001) −0.0001 (− 0.0002, − 0.0001) −0.00009 (− 0.0001, − 0.00002) −0.0001 (− 0.0001, − 0.00009) 0.0002 (− 0.00001, 0.0004) −0.0001 (− 0.0004, 0.0001)
Total PCB (ppb) 0.0057 (−0.0111, 0.0225) 0.0181 (− 0.0013, 0.0377) 0.0297 (0.0136, 0.0458) − 0.0027 (− 0.0154, 0.0099) −0.0402 (− 0.1015, 0.0210) −0.1215 (− 0.2001, − 0.0429)
2 Total PBB (ppb) 0.0080 (− 0.0036, 0.0197) 0.0173 (0.0038, 0.0308) −0.0141 (− 0.0252, − 0.0029) 0.0190 (0.0103, 0.0278) 0.0240 (− 0.0184, 0.0665) 0.1257 (0.0715, 0.1800)
Current Age (years) − 0.00027 (− 0.0016, 0.0010) −0.0063 (− 0.0079, − 0.0047) 0.0006 (− 0.0006, 0.0019) −0.0034 (− 0.0044, − 0.0024) 0.0031 (− 0.0018, 0.0081) −0.0170 (− 0.0233, − 0.0106)
Sex −0.0434 (− 0.0749, − 0.0118) −0.0105 (− 0.0471, 0.0260) −0.0016 (− 0.0318, 0.0284) 0.0457 (0.0220, 0.0693) 0.0321 (− 0.0828, 0.1471) 0.1759 (0.0290, 0.3228)
Lipids (mg/dL) −0.00008 (− 0.0001, − 0.00001) −0.0001 (− 0.0002, − 0.0001) −0.00009 (− 0.0001, − 0.00002) −0.0001 (− 0.0001, − 0.00009) 0.0002 (− 0.00001, 0.0004) −0.0001 (− 0.0004, 0.0001)
Total PCB (ppb) 0.0055 (−0.0112, 0.0224) 0.0177 (− 0.0017, 0.0372) 0.0298 (0.0138, 0.0459) − 0.0031 (− 0.0157, 0.0094) −0.0403 (− 0.0101, 0.0210) −0.1234 (− 0.2018, − 0.0451)
Age exposed ×
Total PBB
−0.0002 (− 0.0009, 0.0003) −0.0008 (− 0.0016, − 0.00007) 0.0002 (− 0.0004, 0.0008) −0.0007 (− 0.0012, − 0.0002) −0.0001 (− 0.0026, 0.0022) −0.0038 (− 0.0069, − 0.0006)