Table 3 Regression coefficients from the association of PBB exposure and thyroid hormone levels in total study population
|  | Total T4 (μ g/dL) | Total T3 (ng/mL) | Free T4 (ng/dL) | Free T3 (pg/mL) | TSH (μ IU/mL) | Free T3: Free T4 ratio | |
|---|---|---|---|---|---|---|---|
Model | Variables | β (95% CI) | β (95% CI) | β (95% CI) | β (95% CI) | β (95% CI) | β (95% CI) |
1 | Total PBB (ppb) | 0.0048 (− 0.0041, 0.0139) | 0.0079 (− 0.0025, 0.0184) | − 0.0116(− 0.0202, − 0.0030) | 0.0104 (0.0036, 0.0172) | 0.0218 (− 0.0110,0.0547) | 0.0840 (0.0418, 0.1262) |
Current Age (years) | − 0.0006 (− 0.0013, 0.0012) | −0.0056 (− 0.0071, − 0.0042) | 0.0005 (− 0.0006, 0.0017) | − 0.0028 (− 0.0038, − 0.0019) | 0.0032 (− 0.0013,0.0078) | −0.0141 (− 0.0200, − 0.0082) | |
Sex | −0.0449 (− 0.0763, − 0.0136) | −0.0154 (− 0.0515, 0.0212) | −0.0004 (− 0.0304, 0.0294) | 0.0414 (0.0178, 0.0651) | 0.0311 (− 0.0830, 0.1452) | 0.1555 (0.0091, 0.3020) | |
Lipids (mg/dL) | −0.00008 (− 0.0001, − 0.00001) | −0.0001 (− 0.0002, − 0.0001) | −0.00009 (− 0.0001, − 0.00002) | −0.0001 (− 0.0001, − 0.00009) | 0.0002 (− 0.00001, 0.0004) | −0.0001 (− 0.0004, 0.0001) | |
Total PCB (ppb) | 0.0057 (−0.0111, 0.0225) | 0.0181 (− 0.0013, 0.0377) | 0.0297 (0.0136, 0.0458) | − 0.0027 (− 0.0154, 0.0099) | −0.0402 (− 0.1015, 0.0210) | −0.1215 (− 0.2001, − 0.0429) | |
2 | Total PBB (ppb) | 0.0080 (− 0.0036, 0.0197) | 0.0173 (0.0038, 0.0308) | −0.0141 (− 0.0252, − 0.0029) | 0.0190 (0.0103, 0.0278) | 0.0240 (− 0.0184, 0.0665) | 0.1257 (0.0715, 0.1800) |
Current Age (years) | − 0.00027 (− 0.0016, 0.0010) | −0.0063 (− 0.0079, − 0.0047) | 0.0006 (− 0.0006, 0.0019) | −0.0034 (− 0.0044, − 0.0024) | 0.0031 (− 0.0018, 0.0081) | −0.0170 (− 0.0233, − 0.0106) | |
Sex | −0.0434 (− 0.0749, − 0.0118) | −0.0105 (− 0.0471, 0.0260) | −0.0016 (− 0.0318, 0.0284) | 0.0457 (0.0220, 0.0693) | 0.0321 (− 0.0828, 0.1471) | 0.1759 (0.0290, 0.3228) | |
Lipids (mg/dL) | −0.00008 (− 0.0001, − 0.00001) | −0.0001 (− 0.0002, − 0.0001) | −0.00009 (− 0.0001, − 0.00002) | −0.0001 (− 0.0001, − 0.00009) | 0.0002 (− 0.00001, 0.0004) | −0.0001 (− 0.0004, 0.0001) | |
Total PCB (ppb) | 0.0055 (−0.0112, 0.0224) | 0.0177 (− 0.0017, 0.0372) | 0.0298 (0.0138, 0.0459) | − 0.0031 (− 0.0157, 0.0094) | −0.0403 (− 0.0101, 0.0210) | −0.1234 (− 0.2018, − 0.0451) | |
Age exposed × Total PBB | −0.0002 (− 0.0009, 0.0003) | −0.0008 (− 0.0016, − 0.00007) | 0.0002 (− 0.0004, 0.0008) | −0.0007 (− 0.0012, − 0.0002) | −0.0001 (− 0.0026, 0.0022) | −0.0038 (− 0.0069, − 0.0006) | |