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Table 1 Description of participants with current asthma at baseline (EGEA2) according to change in current asthma between EGEA2 to EGEA3

From: Does the oxidative stress play a role in the associations between outdoor air pollution and persistent asthma in adults? Findings from the EGEA study

  All participants Participants with remittent asthma Participants with persistent asthma P-value
N 204 43 161  
Age (years), mean ± SD 39.3 ± 16.9 36.7 ± 15.3 40.0 ± 17.3 0.26
Male, n (%) 99 (48.5) 16 (37.2) 83 (51.6) 0.09
Smoking status, n (%)
 Never-smoker 109 (53.4) 22 (51.2) 87 (54.0) 0.52
 Ex-smoker 46 (22.6) 8 (18.6) 38 (23.6)
 Current smoker 49 (24.0) 13 (30.2) 36 (22.4)
BMI (kg/m2), mean ± SD n = 203 23.4 ± 3.99 n = 160 0.40
23.8 ± 3.84 23.9 ± 3.81
Socioprofessional category, n (%)
 Unemployed 32 (15.7) 5 (11.6) 27 (16.8) 0.37
 Manager 64 (31.4) 12 (27.9) 52 (32.3)
 Technician 88 (43.1) 19 (44.2) 69 (42.8)
 Manual worker 20 (9.8) 7 (16.3) 13 (8.1)
Asthma onset years, mean ± SD N = 195 N = 39 N = 156 0.40
14.8 ± 14.7 16.6 ± 14.6 14.4 ± 14.7
Poor controlled asthmaa, n (%) N = 190 N = 38 N = 152 0.007
102 (53.7) 13 (34.2) 89 (58.6)
Use of inhaled corticosteroids, n (%) N = 200 N = 41 N = 159 0.009
132 (66.0) 20 (48.8) 112 (70.4)
Symptom score of asthmab, n (%) N = 199 N = 40 N = 159  
 0 20 (10.0) 9 (22.5) 11 (6.9) 0.005
 1–2 30 (15.1) 8 (20.0) 22 (13.8)
 >2 149 (74.9) 23 (57.5) 126 (79.3)
Plasma FlOPs levels (RFU/mL), GM (q1-q3) 92.0 (79.5–104.7) 85.6 (76.0–96.5) 93.8 (79.9–104.8) 0.02
Residence time (years), mean ± SD 11.7 ± 10.2 (0–42) 10.3 ± 8.90 (0–31) 12.1 ± 10.5 (0–42) 0.31
Air pollutant levels and traffic metricsc, mean ± SD
 NO2 27.9 ± 13.9 29.7 ± 15.3 27.4 ± 13.5 0.34
 NOX 49.7 ± 32.7 53.2 ± 38.4 48.8 ± 31.0 0.44
 PM10 25.0 ± 4.07 25.1 ± 3.71 24.9 ± 4.18 0.88
 PM2.5 15.0 ± 2.04 15.5 ± 1.96 14.9 ± 2.05 0.20
 Traffic load 1,755,353 ± 4,718,630 1,672,062 ± 4,007,561 1,777,599 ± 4,902,148 0.90
 Traffic intensity 7307 ± 13,109 7027 ± 11,360 7382 ± 13,569 0.87
 O3 43.9 ± 4.62 43.1 ± 4.08 44.2 ± 4.74 0.15
 O3-summer 65.4 ± 6.20 64.7 ± 6.41 65.6 ± 6.14 0.38
  1. SD standard deviation, BMI body mass index, FlOPs fluorescent oxidation products, GM geometric mean; q1-q3: 25th and 75th percentiles of the GM
  2. aDefined according to GINA 2015 guidelines and from participants with partly controlled asthma or uncontrolled asthma (see Additional file 1)
  3. bMore details in Additional file 1
  4. cPollutant levels in μg/m3, traffic load in vehicles/day x meters, and traffic intensity in vehicles/day