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Table 1 Description of participants with current asthma at baseline (EGEA2) according to change in current asthma between EGEA2 to EGEA3

From: Does the oxidative stress play a role in the associations between outdoor air pollution and persistent asthma in adults? Findings from the EGEA study

 

All participants

Participants with remittent asthma

Participants with persistent asthma

P-value

N

204

43

161

 

Age (years), mean ± SD

39.3 ± 16.9

36.7 ± 15.3

40.0 ± 17.3

0.26

Male, n (%)

99 (48.5)

16 (37.2)

83 (51.6)

0.09

Smoking status, n (%)

 Never-smoker

109 (53.4)

22 (51.2)

87 (54.0)

0.52

 Ex-smoker

46 (22.6)

8 (18.6)

38 (23.6)

 Current smoker

49 (24.0)

13 (30.2)

36 (22.4)

BMI (kg/m2), mean ± SD

n = 203

23.4 ± 3.99

n = 160

0.40

23.8 ± 3.84

23.9 ± 3.81

Socioprofessional category, n (%)

 Unemployed

32 (15.7)

5 (11.6)

27 (16.8)

0.37

 Manager

64 (31.4)

12 (27.9)

52 (32.3)

 Technician

88 (43.1)

19 (44.2)

69 (42.8)

 Manual worker

20 (9.8)

7 (16.3)

13 (8.1)

Asthma onset years, mean ± SD

N = 195

N = 39

N = 156

0.40

14.8 ± 14.7

16.6 ± 14.6

14.4 ± 14.7

Poor controlled asthmaa, n (%)

N = 190

N = 38

N = 152

0.007

102 (53.7)

13 (34.2)

89 (58.6)

Use of inhaled corticosteroids, n (%)

N = 200

N = 41

N = 159

0.009

132 (66.0)

20 (48.8)

112 (70.4)

Symptom score of asthmab, n (%)

N = 199

N = 40

N = 159

 

 0

20 (10.0)

9 (22.5)

11 (6.9)

0.005

 1–2

30 (15.1)

8 (20.0)

22 (13.8)

 >2

149 (74.9)

23 (57.5)

126 (79.3)

Plasma FlOPs levels (RFU/mL), GM (q1-q3)

92.0 (79.5–104.7)

85.6 (76.0–96.5)

93.8 (79.9–104.8)

0.02

Residence time (years), mean ± SD

11.7 ± 10.2 (0–42)

10.3 ± 8.90 (0–31)

12.1 ± 10.5 (0–42)

0.31

Air pollutant levels and traffic metricsc, mean ± SD

 NO2

27.9 ± 13.9

29.7 ± 15.3

27.4 ± 13.5

0.34

 NOX

49.7 ± 32.7

53.2 ± 38.4

48.8 ± 31.0

0.44

 PM10

25.0 ± 4.07

25.1 ± 3.71

24.9 ± 4.18

0.88

 PM2.5

15.0 ± 2.04

15.5 ± 1.96

14.9 ± 2.05

0.20

 Traffic load

1,755,353 ± 4,718,630

1,672,062 ± 4,007,561

1,777,599 ± 4,902,148

0.90

 Traffic intensity

7307 ± 13,109

7027 ± 11,360

7382 ± 13,569

0.87

 O3

43.9 ± 4.62

43.1 ± 4.08

44.2 ± 4.74

0.15

 O3-summer

65.4 ± 6.20

64.7 ± 6.41

65.6 ± 6.14

0.38

  1. SD standard deviation, BMI body mass index, FlOPs fluorescent oxidation products, GM geometric mean; q1-q3: 25th and 75th percentiles of the GM
  2. aDefined according to GINA 2015 guidelines and from participants with partly controlled asthma or uncontrolled asthma (see Additional file 1)
  3. bMore details in Additional file 1
  4. cPollutant levels in μg/m3, traffic load in vehicles/day x meters, and traffic intensity in vehicles/day
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Environmental Health

ISSN: 1476-069X