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Table 3 Mean DNA methylation in sperm by exposure group in 37 candidate CpG loci

From: Serum dioxin and DNA methylation in the sperm of operation ranch hand veterans exposed to Agent Orange

Gene CpG Russian Low Exposure Group Russian High Exposure Group Ranch Hand
Low Exposure
Ranch Hand High Exposure P-value FDR adjusted p-value
SAMD11 cg06624358 0.58 0.92 0.66 0.61 0.72 0.81
SAMD11 cg14156792 0.51 0.97 0.60 0.55 0.77 0.81
SAMD11 cg01727431 0.59 1 0.59 0.53 0.67 0.80
SAMD11 cg02439789 0.46 0.83 0.58 0.49 0.51 0.80
PGBD5 cg11570508 0.92 0.72 0.97 0.92 0.047 0.35
PGBD5 cg11226042 0.97 0.58 0.93 0.87 0.039 0.35
PGBD5 cg22875527 0.95 0.61 0.95 0.89 0.027 0.5
CCNY cg05701548 0.14 0.38 0.57 0.55 0.77 0.81
RBP3 cg07070043 0.76 0.34 0.66 0.56 0.035 0.35
  cg26066724 0.88 0.32 0.75 0.65 0.34 0.63
  cg07458849 0.91 0.80 0.88 0.87 0.87 0.87
SLC5A10 cg04585390 0.60 0.35 0.58 0.52 0.34 0.63
MBP cg00706570 0.76 0.40 0.72 0.47 0.005 0.185
  cg06167221 0.69 0.80 0.79 0.69 0.12 0.40
  cg00593773 0.61 0.82 0.85 0.77 0.10 0.40
KCNN1 cg21491340 0.17 0.07 0.38 0.30 0.096 0.40
KCNN1 cg21491340 0.14 0.05 0.38 0.30 0.096 0.40
FBLN7 cg11229230 0.83 0.96 0.98 0.97 0.20 0.60
DGKD cg24933152 1 0.92 0.9778 0.9818 0.060 0.37
FAM83C cg12170299 0.78 0.72 0.67 0.63 0.27 0.63
FAM83C cg11133013 0.858 0.63 0.73 0.64 0.21 0.60
C21orf29 cg12061357 0.61 0.25 0.60 0.51 0.12 0.40
  cg26311420 0.56 0.15 0.40 0.45 0.66 0.80
  cg26311420 0.5 0.13 0.40 0.45 0.66 0.80
RBM33 cg14353208 0.82 0.99 0.98 0.97 0.48 0.80
RBM33 cg07262012 0.80 0.97 0.96 0.96 0.53 0.80
  cg14720951 0.28 0.14 0.13 0.17 0.34 0.63
  cg06182811 0.75 0.73 0.69 0.74 0.31 0.63
  cg06182811 0.85 0.74 0.69 0.74 0.31 0.63
  cg19673480 0.83 0.64 0.77 0.79 0.64 0.80
  cg19673480 0.82 0.59 0.77 0.79 0.64 0.80
  cg23541013 0.71 0.44 0.72 0.77 0.33 0.63
  cg01695620 0.74 0.61 0.83 0.87 0.43 0.76
  cg15690180 0.55 0.19 0.46 0.49 0.77 0.81
FLJ43860 cg12732638 0.65 0.84 0.84 0.85 0.79 0.81
PLEC1 cg04247530 0.86 0.94 0.84 0.82 0.55 0.80
TBC1D2 cg14049807 0.06 0.26 0.43 0.39 0.62 0.80