Cumulative solar ultraviolet radiation exposure and basal cell carcinoma of the skin in a nationwide US cohort using satellite and ground-based measures

Table 2 Curvature in exposure response of absolute risk of basal cell carcinoma (BCC) with ultraviolet radiation (UVR) cumulative radiant exposure, using AVGLO and NASA TOMS measures of UVR among 63,912 white technologists^c

Model	Linear excess absolute risk per MJ/cm² per 10⁴ person year (+ 95% CI)	Quadratic excess absolute risk per [MJ/cm²]² per 10⁴ person year (+ 95% CI)	p-value	AIC
AVGLO
Linear	8.48 (5.22, 11.1)		< 0.001^a	11,926.4
Linear-quadratic	−0.11 (−5.17, 4.59)	13.06 (7.15, 18.9)	< 0.001^b	11,910.2
NASA TOMS
Linear	10.15 (6.67, 13.1)		< 0.001^a	11,920.7
Linear-quadratic	3.34 (−2.91, 8.54)	10.1 (4.00, 16.3)	0.001^b	11,912.1

^atest for departure of UVR linear exposure-response from null
^btest for departure of UVR linear-quadratic exposure-response from linearity
^cAll analysis used linear-quadratic model (S1’) with adjustment to the baseline BCC rate for baseline questionnaire, ln [age], birth year, [birth year]², [birth year]³, [birth year]⁴, [birth year]⁵

ISSN: 1476-069X