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Table 1 Characteristics of study participants (n = 100,436) a by categories of skincare product use

From: Use of skincare products and risk of cancer of the breast and endometrium: a prospective cohort study

CharacteristicsNon-usersLight usersModerate usersFrequent usersHeavy users
n184036,59825,71834,2032077
% skin creamed per day0–0.0010.002- < 35.035.0- < 65.065.0- < 115.0115.0–200
Incident cases of breast cancer (n)651176801108858
Breast cancer subtype, % b
ER+83.183.885.384.184.5
ER-15.413.912.112.915.5
Incident cases of endometrial cancer (n)152611412169
Age at enrollment (years), mean ± SD54.8 ± 5.054.3 ± 4.854.9 ± 4.854.8 ± 4.854.8 ± 4.8
Education (years), %
< 1027.215.917.015.415.1
10–1230.432.136.436.134.8
> 1242.451.946.548.550.1
BMI, %     
Under−/Normal weight36.650.756.760.566.4
Overweight33.434.832.730.725.7
Obese30.014.510.68.87.9
Menopausal status at enrollment, %
Pre14.215.713.013.413.4
Peri9.210.39.59.48.9
Post72.468.672.271.572.1
Unknown4.25.45.25.75.6
Age at menarche, mean ± SD13.2 ± 1.513.3 ± 1.413.3 ± 1.413.2 ± 1.413.2 ± 1.5
Age at first full term pregnancy, mean ± SD23.9 ± 4.624.4 ± 4.724.0 ± 4.424.0 ± 4.423.9 ± 4.4
Parity, %
010.310.29.39.210.4
1–247.353.356.759.458.3
≥342.436.633.931.431.3
OC use, %
Never48.240.338.136.036.4
Former51.359.261.463.462.8
Current0.50.50.50.60.8
MHT use, %
Never69.763.756.753.750.8
Former21.423.527.427.227.3
Current8.912.816.019.021.8
IUD use, %
Ever7.711.611.912.212.7
Smoking, %
Never37.436.032.431.031.6
Former30.940.843.945.443.6
Current31.723.223.723.624.8
Physical activity, %
Low37.624.819.816.514.6
Moderate34.841.842.438.932.6
High27.633.437.844.652.8
Alcohol intake (g/day), mean ± SD2.7 ± 4.23.7 ± 4.3)4.1 ± 4.24.4 ± 4.34.2 ± 4.4
  1. SD standard deviation, ER estrogen receptor, BMI body mass index, OC oral contraceptive, MHT menopausal hormone therapy, IUD intrauterine device
  2. a6542 participants had missing values on skincare product use
  3. bPercentage of ER+/ER- subtypes does not add up to 100 due to missing values on hormone receptor status