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Table 1 Characteristics of study participants (n = 100,436) a by categories of skincare product use

From: Use of skincare products and risk of cancer of the breast and endometrium: a prospective cohort study

Characteristics

Non-users

Light users

Moderate users

Frequent users

Heavy users

n

1840

36,598

25,718

34,203

2077

% skin creamed per day

0–0.001

0.002- < 35.0

35.0- < 65.0

65.0- < 115.0

115.0–200

Incident cases of breast cancer (n)

65

1176

801

1088

58

Breast cancer subtype, % b

ER+

83.1

83.8

85.3

84.1

84.5

ER-

15.4

13.9

12.1

12.9

15.5

Incident cases of endometrial cancer (n)

15

261

141

216

9

Age at enrollment (years), mean ± SD

54.8 ± 5.0

54.3 ± 4.8

54.9 ± 4.8

54.8 ± 4.8

54.8 ± 4.8

Education (years), %

< 10

27.2

15.9

17.0

15.4

15.1

10–12

30.4

32.1

36.4

36.1

34.8

> 12

42.4

51.9

46.5

48.5

50.1

BMI, %

     

Under−/Normal weight

36.6

50.7

56.7

60.5

66.4

Overweight

33.4

34.8

32.7

30.7

25.7

Obese

30.0

14.5

10.6

8.8

7.9

Menopausal status at enrollment, %

Pre

14.2

15.7

13.0

13.4

13.4

Peri

9.2

10.3

9.5

9.4

8.9

Post

72.4

68.6

72.2

71.5

72.1

Unknown

4.2

5.4

5.2

5.7

5.6

Age at menarche, mean ± SD

13.2 ± 1.5

13.3 ± 1.4

13.3 ± 1.4

13.2 ± 1.4

13.2 ± 1.5

Age at first full term pregnancy, mean ± SD

23.9 ± 4.6

24.4 ± 4.7

24.0 ± 4.4

24.0 ± 4.4

23.9 ± 4.4

Parity, %

0

10.3

10.2

9.3

9.2

10.4

1–2

47.3

53.3

56.7

59.4

58.3

≥3

42.4

36.6

33.9

31.4

31.3

OC use, %

Never

48.2

40.3

38.1

36.0

36.4

Former

51.3

59.2

61.4

63.4

62.8

Current

0.5

0.5

0.5

0.6

0.8

MHT use, %

Never

69.7

63.7

56.7

53.7

50.8

Former

21.4

23.5

27.4

27.2

27.3

Current

8.9

12.8

16.0

19.0

21.8

IUD use, %

Ever

7.7

11.6

11.9

12.2

12.7

Smoking, %

Never

37.4

36.0

32.4

31.0

31.6

Former

30.9

40.8

43.9

45.4

43.6

Current

31.7

23.2

23.7

23.6

24.8

Physical activity, %

Low

37.6

24.8

19.8

16.5

14.6

Moderate

34.8

41.8

42.4

38.9

32.6

High

27.6

33.4

37.8

44.6

52.8

Alcohol intake (g/day), mean ± SD

2.7 ± 4.2

3.7 ± 4.3)

4.1 ± 4.2

4.4 ± 4.3

4.2 ± 4.4

  1. SD standard deviation, ER estrogen receptor, BMI body mass index, OC oral contraceptive, MHT menopausal hormone therapy, IUD intrauterine device
  2. a6542 participants had missing values on skincare product use
  3. bPercentage of ER+/ER- subtypes does not add up to 100 due to missing values on hormone receptor status