Skip to main content

Advertisement

Table 4 Association between duration of pesticide use (in years) and aggressive PCa for those pesticides first reported at follow-up (Phase 2 and Phase 3 questionnaires) in the Agricultural Health Study (AHS)b

From: Pesticide exposure and risk of aggressive prostate cancer among private pesticide applicators

Common nameNon-caseAggressive PCaHR (95% CI)a
Herbicide
 Acetochlor
  Never use15,0976331
  < 9 years1213280.76 (0.52, 1.12)
  ≥ 9 years882301.12 (0.77, 1.63)
  p-trend0.96
 Clopyralid
  Never use16,5046841
  < 5 years46990.66 (0.34, 1.28)
  ≥ 5 years565150.88 (0.53, 1.47)
  p-trend0.39
 Glufosinate-ammonium
  Never use16,5166831
  < 5 years613120.67 (0.38, 1.20)
  ≥ 5 years526161.03 (0.62, 1.70)
  p-trend0.79
 Mesotrione
  Never use16,2846801
  < 4 years753170.82 (0.50, 1.33)
  ≥ 4 years856170.77 (0.48, 1.26)
  p-trend0.22
 Nicosulfuron
  Never use15,9216681
  < 5 years560150.88 (0.53, 1.48)
  ≥ 5 years820210.84 (0.54, 1.30)
  p-trend0.39
 Picloram
  Never use15,8176371
  < 6 years899321.15 (0.80, 1.65)
  ≥ 6 years1145320.79 (0.55, 1.14)
  p-trend0.28
 Rimsulfuron
  Never use16,7176901
  < 4 years333101.00 (0.54, 1.88)
  ≥ 4 years573140.78 (0.46, 1.32)
  p-trend0.39
 Triclopyr
  Never use16,7706901
  < 4 years282100.99 (0.53, 1.85)
  ≥ 4 years848130.44 (0.26, 0.77)
  p-trend0.004
Insecticide
 Cyfluthrin
  Never use16,3806861
  < 6 years803170.71 (0.44, 1.15)
  ≥ 6 years645140.82 (0.48, 1.39)
  p-trend0.22
 Tebupirimfos
  Never use17,0226981
  < 6 years540120.69 (0.39, 1.23)
  ≥ 6 years381121.09 (0.61, 1.93)
  p-trend0.67
  1. aUsing age as the time metric and adjusted for state, birth year, family history of PCa, race, and smoking status
  2. bNumbers add to less than total number of follow-up responders (n = 18,933) due to missing responses for duration of use information