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Table 3 Regression results of ln-transformed lipids versus ln-transformed PFAS among adults 20 to 60 years

From: Associations between perfluoroalkyl substances and serum lipids in a Swedish adult population with contaminated drinking water

 All (n = 1945)Control (n = 130)Total exposed (n = 1815)Recently exposed (n = 1160)
Coefficent (SE)pCoefficent (SE)pCoefficent (SE)pCoefficent (SE)p
Total cholesterolPFOS0.013 (0.0036)< 0.010.058 (0.028)0.040.0091 (0.0044)0.040.035 (0.0089)< 0.01
PFHxS0.011 (0.0029)< 0.010.051 (0.021)0.020.0072 (0.0039)0.060.029 (0.0080)< 0.01
PFOA0.016 (0.0050)< 0.010.042 (0.033)0.20.011 (0.0055)0.050.035 (0.0094)< 0.01
Sum PFASa0.013 (0.0034)< 0.010.075 (0.031)0.020.0084 (0.0043)0.050.032 (0.0086)< 0.01
LDLPFOS0.017 (0.0049)< 0.010.084 (0.041)0.040.012 (0.0060)0.050.050 (0.012)< 0.01
PFHxS0.014 (0.0040)< 0.010.087 (0.031)0.010.0093 (0.0053)0.080.043 (0.011)< 0.01
PFOA0.020 (0.0068)< 0.010.073 (0.048)0.130.013 (0.0075)0.090.047 (0.013)< 0.01
Sum PFAS0.016 (0.0047)< 0.010.12 (0.045)0.010.011 (0.0058)0.070.047 (0.012)< 0.01
HDLPFOS0.013 (0.0046)< 0.010.052 (0.034)0.130.014 (0.0057)0.010.045 (0.012)< 0.01
PFHxS0.0097 (0.0038)0.010.013 (0.026)0.630.011 (0.0051)0.030.036 (0.011)< 0.01
PFOA0.019 (0.0065)< 0.010.045 (0.040)0.250.017 (0.0072)0.020.048 (0.013)< 0.01
Sum PFAS0.012 (0.0045)0.010.040 (0.038)0.290.013 (0.0056)0.020.041 (0.012)< 0.01
TriglyceridePFOS−0.0075 (0.0080)0.35−0.047 (0.080)0.56−0.021 (0.0098)0.03−0.039 (0.020)0.05
PFHxS−0.0029 (0.0066)0.65−0.011 (0.061)0.86−0.015 (0.0086)0.07−0.032 (0.018)0.08
PFOA− 0.011 (0.011)0.32− 0.058 (0.092)0.53−0.019 (0.012)0.12−0.018 (0.021)0.39
Sum PFAS−0.0060 (0.0077)0.44−0.036 (0.088)0.68−0.018 (0.0095)0.05−0.035 (0.019)0.07
total cholesterol/HDL ratioPFOS−0.00010 (0.0047)0.980.0062 (0.044)0.89−0.0051 (0.0057)0.37−0.0099 (0.012)0.40
PFHxS0.0011 (0.0038)0.780.038 (0.033)0.25−0.0039 (0.0050)0.44−0.0072 (0.011)0.50
PFOA−0.0030 (0.0065)0.65−0.0031 (0.050)0.95−0.0066 (0.0071)0.35−0.013 (0.012)0.29
Sum PFAS0.00030 (0.0045)0.950.035 (0.048)0.47−0.0046 (0.0055)0.41−0.0086 (0.011)0.45
  1. Note: All estimates are from regression models with ln-transformed lipids as response, ln-transformed of PFAS as the variables of interest and with additional adjusted for age, sex and BMI (in quartiles)
  2. aSum PFAS: Molar-weight adjusted sum of PFOS, PFHxS and PFOA