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Table 2 OR and 95% CI for lymphoma (all subtypes combined) and B-cell lymphomas in relation to dose and probability of exposure to external (A) and internal (B) ionizing radiation

From: Occupational exposure to ionizing radiation and risk of lymphoma subtypes: results of the Epilymph European case-control study

(A) external radiation and (B) interal radiation

All lymphomas

(N = 2319)

B-cell lymphomas

(N = 1907)

cases/controls

OR

95%CI

cases/controls

OR

95%CI

(A)

 Unexposed

2095/2164

1.0

–

1730/2164

1.0

–

 Ever exposed

224 /255

0.9

0.73–1.08

177/255

0.9

0.75–1.14

Average probability

 Possible

199/228

0.9

0.73–1.08

156/228

0.9

0.74–1.15

 Probable/definite

25/27

0.9

0.53–1.60

21/27

0.9

0.52–1.69

Average dose

 1–2.5 mSv

103/121

0,8

0.62–1.08

85/121

0.9

0.65–1.16

  ≥ 2.6 mSv

121/134

1.0

0.74–1.24

92/134

1.0

0.74–1.30

  ≥ 2.6 mSv, probable/ definite exposure

16/13

1.3

0.60–2.64

12/13

1.2

0.53–2.60

Duration of exposure

  ≤ 11 years

116/131

0.9

0.68–1.15

85/131

0.9

0.68–1.21

  ≥ 12 years

108/124

0.9

0.68–1.17

92/124

0.9

0.71–1.25

Cumulative exposure

 1.75–15.39 mSv-years

119/126

0.9

0.72–1.21

90/126

1.0

0.72–1.27

>  15.4 mSv-years

105/129

0.9

0.65–1.11

87/129

0.9

0.68–1.19

Probable/definite exposure

  ≥ 15.4 mSv-years

16/16

1.0

0.51–2.06

13/16

1.0

0.48–2.12

 

All lymphomas

(N = 2186)

B-cell lymphomas

(N = 1700)

cases/controls

OR

95%CI

cases/controls

OR

95%CI

(B)

 Unexposed

2149/2164

1.0

–

1669/2164

1.0

–

 Ever exposed

37/54

0.7

0.43–1.02

31/54

0.7

0.45–1.12

Average probability

 Possible

13/22

0.6

0.28–1.12

11/22

0.6

0.31–1.33

 Probable/definite

24/32

0.7

0.39–1.11

20/32

0.8

0.43–1.34

Average intensity

 1–2.5 mSv

35/30

1.2

0.70–1.90

29/30

1.1

0.65–1.85

  > 2.5 mSv

2/24

0.1

0.02–0.31

2/24

0.1

0.03–0.50

Duration of exposure

  ≤ 8 years

24/27

0.9

0.49–1.50

19/27

0.9

0.50–1.65

  ≥ 9 years

13/27

0.5

0.24–0.91

12/27

0.5

0.26–1.04

Cumulative exposure

  ≤ 30 mSv-years

21/25

0.8

0.45–1.46

18/25

0.9

0.50–1.71

  > 30 mSv-years

16/29

0.5

0.29–1.00

13/29

0.5

0.27–1.03