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Table 4 Adjusteda odds ratios or percent differences of specific gravity-corrected urinary organophosphate ester metabolite concentrations

From: Predictors and reproducibility of urinary organophosphate ester metabolite concentrations during pregnancy and associations with birth outcomes in an urban population

Characteristics

BCIPP

OR (95% CI)

BDCIPP

% diff (95% CI)

DPHP

% diff (95% CI)

ip-PPP

% diff (95% CI)

tb-PPP

% diff (95% CI)

Sociodemographic

 Maternal age (years; centered)

1.02 (0.95, 1.10)

−4.48 (−7.98, −0.85)

−0.29 (−3.18, 2.69)

−1.17 (− 3.47, 1.18)

1.08 (− 4.82, 7.34)

 Maternal BMI (kg/m2)

0.99 (0.96, 1.03)

3.34 (1.33, 5.39)

0.39 (−1.74, 2.55)

1.25 (− 0.29, 2.81)

1.53 (−3.03, 6.31)

Maternal race/ethnicity

 White, n = 48

1 (ref)

0 (ref)

0 (ref)

0 (ref)

0 (ref)

 Non-white, n = 42

1.43 (0.65, 3.16)

22.5 (−21.5, 91.3)

−28.0 (−52.6, 9.20)

4.58 (− 23.4, 42.8)

−12.0 (−57.2, 81.0)

Maternal education (highest level)

 High school diploma or less, n = 18

1 (ref)

0 (ref)

0 (ref)

0 (ref)

0 (ref)

 Less than Bachelor’s degree, n = 18

0.91 (0.31, 2.66)

13.4 (−35.4, 98.9)

47.0 (−9.81, 139.6)

19.8 (25.3, 92.0)

331.9 (60.9, 1059.5)

 Bachelor’s degree or higher, n = 54

1.22 (0.42, 3.57)

48.9 (−20.9, 180.3)

19.8 (−28.4, 100.5)

63.1 (5.48, 152.1)

81.3 (−46.8, 518.1)

Parity

 Nulliparous, n = 44

1 (ref)

0 (ref)

0 (ref)

0 (ref)

0 (ref)

 Parous, n = 46

0.53 (0.26, 1.10)

31.0 (−11.2, 93.1)

29.8 (−8.88, 85.0)

37.2 (3.74, 81.4)

−7.91 (− 54.8, 87.5)

Trimester

 First (<  13 weeks), n = 27b

1 (ref)

0 (ref)

0 (ref)

0 (ref)

0 (ref)

 Second (13–27 weeks), n = 133

0.80 (0.32, 2.01)

1.14 (− 30.5, 47.2)

86.9 (25.0, 179.6)

3.26 (−23.0, 38.6)

− 41.9 (− 74.3, 31.5)

 Third (28 weeks to delivery), n = 52

0.45 (0.14, 1.45)

−10.8 (− 40.2, 32.8)

108.8 (33.5, 226.7)

− 12.7 (− 40.1, 27.4)

12.1 (−51.0, 156.5)

Time at collection (hours)

 Before 11 am, n = 74b

1 (ref)

0 (ref)

0 (ref)

0 (ref)

0 (ref)

 Between 11 am and 1:59 pm, n = 79

0.71 (0.35, 1.44)

1.05 (−24.9, 36.0)

−2.57 (− 27.1, 30.3)

−7.31 (− 27.7, 18.7)

−36.6 (−64.2, 12.1)

 At or after 2 pm, n = 59

0.59 (0.25, 1.39)

−38.0 (−56.1, − 12.3)

−25.1 (−44.7, 1.44)

−36.7 (− 51.1, − 18.0)

−29.8 (−63.6, 35.1)

Season of sample collection

 Fall, n = 52b

1 (ref)

0 (ref)

0 (ref)

0 (ref)

0 (ref)

 Winter, n = 85

0.64 (0.27, 1.52)

− 24.4 (−44.1, 2.14)

− 17.4 (− 39.8, 13.4)

− 30.3 (−49.8, − 3.38)

−33.9 (−66.7, 31.2)

 Spring, n = 57

0.47 (0.17, 1.29)

4.87 (− 28.3, 53.3)

− 11.2 (− 40.7, 33.1)

4.33 (− 25.4, 45.8)

32.2 (− 41.4, 198.2)

 Summer, n = 18

0.45 (0.15, 1.31)

7.37 (−42.8, 101.5)

22.1 (− 32.0, 119.1)

9.47 (−22.6, 54.9)

− 15.1 (−68.4, 128.5)

Coefficient of determination (R2)

 Sociodemographic only

10.1

27.4

11.1

12.9

12.4

Environmental/Behavioral

 Frequency of vacuuming home

  Never/yearly, n = 17

 

0 (ref)

   

  Monthly, n = 18

 

−58.6 (−77.4, −24.0)

   

  Daily/weekly, n = 55

 

−47.8 (−68.6, −13.3)

   

 Frequency of mopping home

  Never/yearly, n = 19

 

0 (ref)

0 (ref)

0 (ref)

0 (ref)

  Monthly, n = 25

 

−1.04 (−34.5, 49.4)

24.2 (−21.2, 95.7)

−23.8 (−43.0, 1.93)

38.7 (−42.1, 232.2)

  Daily/weekly, n = 46

 

41.7 (− 16.8, 141.0)

20.8 (−21.1, 85.1)

18.2 (− 18.0, 70.3)

23.1 (−52.2, 216.7)

 New furniture (within past year)

  No, n = 68 - 71c

1 (ref)

 

0 (ref)

  

  Yes, n = 19–22

0.67 (0.29, 1.55)

 

31.0 (−9.6, 89.8)

  

 New bedding (within past year)

  No, n = 52 - 54c

1 (ref)

  

0 (ref)

 

  Yes, n = 36–38

0.49 (0.23, 1.04)

  

−23.3 (−41.8, 1.07)

 

 # of televisions in household

   < 2, n = 26

 

0 (ref)

   

   2+, n = 64

 

19.4 (−31.4, 107.6)

   

 # of computers or tablets in household

   < 2, n = 16

 

0 (ref)

0 (ref)

 

0 (ref)

   2+, n = 74

 

15.6 (−31.4, 94.7)

−26.6 (−54.5, 18.3)

 

−33.5 (−75.1, 77.5)

Coefficient of determination (R2)

 Sociodemographic +

     

 Environmental/behavioral

14.0

36.8

13.3

17.4

13.5

  1. Abbreviations: BCIPP Bis(1-chloro-2-propyl) phosphate; BDCIPP Bis(1,3-dichloro-2-propyl) phosphate; CI Confidence interval; diff Difference; DPHP Diphenyl phosphate; ip-PPP Isopropyl phenyl phenyl phosphate; OR Odds ratio; tb-PPP Tert-butyl-phenyl phenyl phosphate
  2. a Percent difference or odds ratio estimated from multivariable linear or logistic regression model estimated by generalized estimating equations with unstructured covariance and robust Huber-White sandwich standard errors
  3. b Sample size within levels of these categorical variables are based on samples, not women, since some provided multiple samples over time
  4. c Number of individuals within category vary by imputation