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Table 1 Incidence rate ratios for determinants (excluding smoking) of all cancers, smoking-relateda and non-smoking-related cancersb

From: Cancer rates not explained by smoking: a county-level analysis

 

All Cancers

All Smoking-related Cancers

All Non-smoking-related Cancers

Variable

IRR

(95% CI)

IRR

(95% CI)

IRR

(95% CI)

Age at diagnosis

 20–24

1

(Ref.)

1

(Ref.)

1

(Ref.)

 25–29

1.64

(1.61–1.68)

2.09

(2.00–2.18)

1.56

(1.53–1.60)

 30–34

2.56

(2.51–2.61)

4.03

(3.88–4.19)

2.30

(2.25–2.35)

 35–39

3.86

(3.79–3.93)

6.80

(6.56–7.05)

3.31

(3.25–3.38)

 40–44

6.12

(6.02–6.23)

11.98

(11.57–12.42)

5.01

(4.91–5.11)

 45–49

9.85

(9.68–10.01)

21.76

(21.01–22.53)

7.55

(7.41–7.70)

 50–54

15.81

(15.54–16.07)

39.80

(38.45–41.19)

11.34

(11.13–11.56)

 55–59

23.44

(23.06–23.83)

59.41

(57.41–61.48)

16.84

(16.53–17.15)

 60–64

33.25

(32.71–33.80)

87.89

(84.94–90.95)

23.60

(23.17–24.04)

 65–69

46.43

(45.68–47.20)

130.40

(126.02–134.93)

31.83

(31.26–32.42)

 70–74

55.36

(54.46–56.28)

171.15

(165.40–177.10)

35.93

(35.27–36.60)

 75–79

62.19

(61.18–63.23)

208.92

(201.90–216.19)

38.17

(37.47–38.89)

 80–84

65.10

(64.03–66.19)

232.89

(225.04–241.01)

38.07

(37.36–38.80)

Gender

 Women

1

(Ref.)

1

(Ref.)

1

(Ref.)

 Men

1.16

(1.16–1.17)

1.61

(1.60–1.61)

0.96

(0.96–0.97)

Year of diagnosis

 2006

1

(Ref.)

1

(Ref.)

1

(Ref.)

 2007

1.01

(1.00–1.03)

0.99

(0.97–1.02)

1.03

(1.01–1.04)

 2008

1.01

(0.99–1.02)

0.99

(0.96–1.02)

1.01

(1.00–1.03)

 2009

1.00

(0.98–1.02)

0.98

(0.95–1.00)

1.01

(0.99–1.03)

 2010

0.98

(0.97–1.00)

0.95

(0.93–0.98)

1.00

(0.98–1.02)

 2011

0.98

(0.97–1.00)

0.94

(0.92–0.97)

1.00

(0.99–1.01)

 2012

0.97

(0.96–0.99)

0.95

(0.93–0.98)

0.98

(0.96–0.99)

 2013

0.96

(0.94–0.97)

0.93

(0.91–0.96)

0.97

(0.95–0.98)

 2014

0.97

(0.96–0.99)

0.95

(0.92–0.97)

0.97

(0.96–0.99)

 2015

0.97

(0.96–0.99)

0.93

(0.91–0.96)

0.98

(0.97–1.00)

 2016

0.95

(0.94–0.97)

0.90

(0.88–0.93)

0.97

(0.96–0.99)

  1. Abbreviations: CI Confidence interval; IRR Incidence rate ratio; Ref Reference
  2. a Smoking-related cancer sites classified according to [8].
  3. b Estimates from three negative binomial regression models with random intercept on county and random slope on year. SEER 18 registries, 2006–2016, Alaska Native Tumor Registry excluded because of the lack of information on county