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Fig. 4 | Environmental Health

Fig. 4

From: Perinatal oral exposure to low doses of bisphenol A, S or F impairs immune functions at intestinal and systemic levels in female offspring mice

Fig. 4

Perinatal exposure to BPA provokes intestinal Th1/Th17 immune response in adult offspring mice. Flow cytometry analysis of Th1 CD3+IFN-γ+T-bet+ (a) or Th17 CD3+RORγt+IL-17 + (c) lymphocytes from siLP. IFN-γ (b) or IL-17 (d) level assessed by ELISA after anti-CD3/CD28 in vitro restimulation of isolated lymphocytes from siLP offspring mice at PND70. (e) Proportion of CD4+CD25+FoxP3+ Treg cells in siLP of offspring mice at PND70. * P < 0.05 vs. vehicle group. n = 5–14

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