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Table 1 Population characteristics and placental PBDE levels during mid-gestation at the Women’s Options Center (WOC) in Northern California, 2014–16 (n = 135)

From: Association of polybrominated diphenyl ether (PBDE) levels with biomarkers of placental development and disease during mid-gestation

  

Wet-weight BDE-47

Lipid-adjusted BDE-47

Wet-weight ∑ PBDE4a

Lipid-adjusted ∑ PBDE4a

Population Characteristic

n (%)

GM (95% CI)

p-Valueb

GM (95% CI)

p-Valueb

GM (95% CI)

p-Valueb

GM (95% CI)

p-Valueb

Maternal Age

  < 20 years

19 (14)

0.10 (0.08, 0.14)

0.910

11.1 (8.4, 14.6)

0.945

0.20 (0.16, 0.26)

0.922

21.6 (16.9, 27.5)

0.893

 20–24 years

58 (43)

0.10 (0.08, 0.14)

 

10.8 (7.8, 14.9)

 

0.20 (0.15, 0.27)

 

20.9 (15.7, 27.8)

 

 25–29 years

30 (22)

0.10 (0.07, 0.14)

 

11.1 (7.7, 15.8)

 

0.20 (0.14, 0.27)

 

22.1 (16.1, 30.4)

 

  ≥ 30 years

29 (21)

0.10 (0.07, 0.15)

 

11.3 (7.8, 16.2)

 

0.19 (0.14, 0.26)

 

21.0 (15.3, 29.0)

 

Gestational Age

  < 19 weeks

37 (27)

0.11 (0.09, 0.13)

0.255

11.6 (9.5, 14.1)

0.601

0.21 (0.18, 0.25)

0.440

22.4 (18.8, 26.8)

0.756

 19–21 weeks

51 (38)

0.11 (0.09, 0.14)

 

11.3 (8.7, 14.8)

 

0.21 (0.16, 0.26)

 

21.3 (16.8, 26.9)

 

  ≥ 21 weeks

48 (35)

0.09 (0.07, 0.12)

 

10.2 (7.8, 13.4)

 

0.18 (0.15, 0.23)

 

20.5 (16.2, 26.0)

 

Body Mass Index (BMI)

 Normal/Under (< 25 kg/m2)

59 (43)

0.10 (0.08, 0.11)

0.602

10.8 (9.2, 12.7)

0.795

0.19 (0.16, 0.22)

0.594

21.1 (18.3, 24.3)

0.652

 Overweight (25–30 kg/m2)

38 (28)

0.11 (0.09, 0.14)

 

10.6 (8.1, 13.7)

 

0.21 (0.17, 0.26)

 

20.2 (16.1, 25.5)

 

 Obese (≥ 30 kg/m2)

39 (29)

0.10 (0.08, 0.13)

 

11.6 (9.0, 15.0)

 

0.20 (0.16, 0.25)

 

22.7 (18.2, 28.4)

 

Parity

 0 live births

55 (40)

0.09 (0.08, 0.11)

0.309

9.9 (8.4, 11.6)

0.240

0.19 (0.16, 0.21)

0.443

19.6 (16.9, 22.6)

0.325

  ≥ 1 live births

81 (60)

0.11 (0.09, 0.13)

 

11.9 (9.6, 14.7)

 

0.21 (0.17, 0.25)

 

22.6 (18.7, 27.4)

 

Fetal Sex

 Male

73 (54)

0.10 (0.09, 0.12)

0.955

10.2 (8.8, 11.8)

0.379

0.20 (0.18, 0.23)

0.942

20.4 (18.0, 23.3)

0.659

 Female

63 (46)

0.10 (0.09, 0.13)

 

11.9 (9.6, 14.7)

 

0.20 (0.16, 0.23)

 

22.3 (18.5, 26.9)

 

Education

  ≤ High School

67 (49)

0.11 (0.10, 0.13)

0.260

11.9 (10.2, 13.8)

0.415

0.22 (0.19, 0.25)

0.177

23.1 (20.2, 26.3)

0.308

  ≥ Some college

68 (50)

0.09 (0.08, 0.12)

 

10.3 (8.3, 12.7)

 

0.18 (0.15, 0.22)

 

19.9 (16.5, 24.0)

 

Insurance

 Public

98 (72)

0.11 (0.10, 0.12)

0.364

11.7 (10.3, 13.3)

0.159

0.21 (0.19, 0.23)

0.222

22.7 (20.4, 25.3)

0.066

 Private/Self-pay

37 (27)

0.09 (0.07, 0.11)

 

9.3 (7.3, 11.7)

 

0.17 (0.14, 0.21)

 

17.7 (14.4, 21.8)

 

Race/ethnicity

 Latina/Hispanic

45 (33)

0.10 (0.09, 0.12)

0.102

10.2 (8.6, 12.1)

0.038

0.19 (0.16, 0.22)

0.011

18.8 (16.2, 21.8)

0.001

 Non-Hispanic Black

31 (23)

0.12 (0.09, 0.16)

 

13.7 (10.4, 17.9)

 

0.24 (0.19, 0.31)

 

27.6 (21.9, 34.8)

 

 Non-Hispanic White

20 (15)

0.09 (0.07, 0.13)

 

10.6 (7.8, 14.4)

 

0.18 (0.14, 0.23)

 

20.2 (15.4, 26.3)

 

 Asian/Pacific Islander

17 (12)

0.09 (0.06, 0.12)

 

9.2 (6.6, 12.7)

 

0.16 (0.12, 0.21)

 

17.0 (12.8, 22.6)

 

Birth Country

 U.S. born

71 (52)

0.11 (0.10, 0.13)

0.114

11.8 (10.3, 13.6)

0.222

0.21 (0.19, 0.23)

0.009

22.4 (19.9, 25.3)

0.025

 Foreign born

9 (7)

0.07 (0.05, 0.11)

 

8.3 (5.5, 12.4)

 

0.12 (0.08, 0.17)

 

13.5 (9.4, 19.3)

 

Collection Year

 2014

33 (24)

0.11 (0.09, 0.13)

0.032

13.8 (11.3, 16.9)

0.004

0.20 (0.17, 0.24)

0.125

24.8 (20.7, 29.7)

0.037

 2015

93 (68)

0.10 (0.08, 0.12)

 

9.8 (7.7, 12.3)

 

0.19 (0.16, 0.24)

 

19.6 (15.9, 24.3)

 

 2016

10 (7)

0.16 (0.10, 0.26)

 

15.9 (10.0, 25.3)

 

0.29 (0.19, 0.43)

 

28.0 (18.4, 42.5)

 

Total (pooled)b

135 (100)

0.10 (0.09; 0.03–0.92)

 

11.0 (9.7; 3.1–107)

 

0.20 (0.15; 0.07–1.3)

 

21.3 (16.4; 5.8–152)

 
  1. GM Geometric mean, IQR Interquartile range (25th–75th percentile)
  2. † Number (%) missing = 56 (41), 1 (0.7), 1 (0.7), and 23 (17) for birth country, education, insurance, and race/ethnicity, respectively
  3. a∑ PBDE4 = BDE-47 + BDE-99 + BDE-100 + BDE-153
  4. bP-values from ANOVA test of mean difference in Ln PBDE levels between population characteristic subgroups. P < 0.10 bolded
  5. cSummary statistics of placental PBDE levels in total (pooled) study population, including: GM (IQR; Min–Max)