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Table 4 Kidney function parameters in early and late pregnancy together with the relative changes that occurred during pregnancy

From: Pregnancy-induced changes in serum concentrations of perfluoroalkyl substances and the influence of kidney function

  Early Late   Change during pregnancy, (%)
Median 5th and 95th percentiles Median 5th and 95th percentiles p-value Median 5th and 95th percentiles
Marker
 Plasma creatinine (μmol/L) 57 45; 67 58 46; 72 0.004 4 −11; 23
 Plasma cystatin C (mg/L) 0.63 0.55; 0.79 1.05 0.77; 1.38 < 0.001 65 26; 116
eGFR (mL/min/1.73m2)
 LMrev 104 90; 120 102 86; 118 0.004 − 2 −12; 8
 CKD-EPIcreatinine 119 102; 131 119 96; 130 0.003 −1 −16; 5
 CAPA 136 104; 160 76 54; 108 < 0.001 −44 −59; −23
 CKD-EPIcystatin C 123 109; 133 76 53; 112 < 0.001 −38 − 57; −12
 Mean of LMrev and CAPA 120 101; 140 89 72; 112 < 0.001 −24 −35; −13
 Mean of CKD-EPIcreatinine and CKD-EPIcystatin C 121 110; 130 97 78; 118 < 0.001 −20 −31; −7
eGFRcystatin C/eGFRcreatininea
 CAPA/LMrev 1.3 1.0; 1.5 0.7 0.5; 1.0 < 0.001 −40 −60; −24
 CKD-EPIcystatin C/CKD-EPIcreatinine 1.0 0.9; 1.1 0.7 0.5; 0.9 < 0.001 −35 −55; −13
  1. aeGFRcystatin C/eGFRcreatinine ≤ 0.6 defines Shrunken pore syndrome