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Table 4 Association between PFAS concentrations (ln-transformed) and high FPG and 1 h-PG in pregnant women

From: Concentrations of perfluoroalkyl and polyfluoroalkyl substances and blood glucose in pregnant women

In-PFAS (ng/ml) FPG(N = 856) 1 h-PG(N = 705)
COR (95% CI) AOR (95% CI) COR (95% CI) AOR (95% CI)
PFHxS 1.00 (0.61, 1.62) 0.89 (0.51, 1.55) 0.92 (0.52, 1.63) 0.92 (0.45, 1.86)
PFOS 1.28 (0.88, 1.85) 1.28 (0.85, 1.93) 1.77 (1.15, 2.72) 1.87 (1.15, 3.05)
PFOA 1.39 (0.86, 2.26) 1.31 (0.77, 2.22) 1.15 (0.67, 1.92) 1.40 (0.75, 2.59)
PFNA 1.54 (1.02, 2.34) 1.55 (0.98, 2.46) 1.74 (1.08, 2.78) 2.15 (1.24, 3.74)
PFDA 1.25 (0.91, 1.71) 1.24 (0.87, 1.76) 1.52 (1.06, 2.17) 1.61 (1.10, 2.44)
PFUdA 0.99 (0.73, 1.34) 0.98 (0.71, 1.35) 1.48 (1.04, 2.12) 1.71 (1.12, 2.62)
PFDoA 1.13 (0.92, 1.39) 1.09 (0.87, 1.37) 1.28 (1.00, 1.65) 1.34 (1.00, 1.81)
PFTrDA 1.04 (0.85, 1.28) 1.12 (0.89, 1.40) 1.12 (0.88, 1.41) 1.13 (0.87, 1.49)
  1. COR crude odds ratio, AOR adjusted odds ratio, CI confidence interval, FPG fasting plasma glucose, 1 h-PG 1 h-plasma glucose after a 50-g oral glucose tolerance test
  2. Models were adjusted for maternal age at enrollment (years), pre-pregnancy BMI (kg/m2), per capita household income, education level, passive smoking, pregnancy complication, history of abortion and stillbirth, and parity
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