Using three statistical methods to analyze the association between exposure to 9 compounds and obesity in children and adolescents: NHANES 2005-2010

Table 3 Association between single exposure and obesity in the NHANES 2005–2010 (N = 2372)

Chemical exposures	Quartile 1	Quartile 2		Quartile 3		Quartile 4		Total
		OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
Phenols
BPA	Ref	0.95 (0.70, 1.30)	0.759	0.92 (0.66, 1.27)	0.595	1.05 (0.75, 1.47)	0.770	1.05 (0.80, 1.38)	0.728
BP-3	Ref	1.00 (0.74, 1.34)	0.984	1.18 (0.87, 1.59)	0.282	0.93 (0.68, 1.28)	0.655	0.98 (0.84, 1.12)	0.738
Paraben
MeP	Ref	0.69 (0.51, 0.92)	0.013	0.65 (0.47, 0.88)	0.006	0.63 (0.45, 0.88)	0.007	0.80 (0.68, 0.94)	0.006
PrP	Ref	1.04 (0.78, 1.40)	0.784	0.82 (0.60, 1.12)	0.218	0.69 (0.49, 0.98)	0.037	0.90 (0.79, 1.03)	0.135
Pesticides
2,5-DCP	Ref	1.49 (1.07, 2.07)	0.017	1.80 (1.30, 2.51)	0.001	2.06 (1.47, 2.89)	0.001	1.25 (1.11, 1.40)	0.001
2,4-DCP	Ref	0.97 (0.70, 1.35)	0.863	1.04 (0.74, 1.45)	0.829	1.11 (0.79, 1.58)	0.536	1.16 (0.97, 1.37)	0.098
Phthalate metabolites
MBzP	Ref	1.07 (0.79, 1.45)	0.683	1.05 (0.76, 1.46)	0.753	0.89 (0.63, 1.27)	0.535	0.96 (0.75, 1.21)	0.705
MEP	Ref	1.04 (0.75, 1.43)	0.824	1.28 (0.92, 1.79)	0.140	1.39 (0.98, 1.98)	0.069	1.28 (1.04, 1.58)	0.022
MiBP	Ref	1.49 (1.08, 2.07)	0.016	1.43 (1.01, 2.03)	0.045	1.62 (1.11, 2.37)	0.013	1.42 (1.07, 1.89)	0.015

NHANES National Health and Nutrition Examination Survey, OR Odds ratio, CI Confidence interval. Total means continuous chemical variable. Multivariable logistic regression was conducted, and odds ratios (ORs) were calculated while comparing the second, third, and fourth quartiles of each chemical with reference to the first exposure quartile (N = 2372). Models were adjusted for age, gender, race, educational levels, family income-to-poverty ratio, caloric intake, serum cotinine and log-transformed creatinine

ISSN: 1476-069X