Using three statistical methods to analyze the association between exposure to 9 compounds and obesity in children and adolescents: NHANES 2005-2010

Table 4 Association between single exposure and BMI z-score in NHANES 2005–2010 (N = 2372)

Chemical exposures	Quartile 1	Quartile 2		Quartile 3		Quartile 4		Total
		β (95%CI)	P value	β (95%CI)	P value	β (95%CI)	P value	β (95%CI)	P value
Phenols
BPA	Ref	0.02 (−0.12, 0.16)	0.772	0.01 (−0.14, 0.15)	0.928	−0.01 (−0.15, 0.15)	0.995	−0.06 (−0.19, 0.06)	0.342
BP-3	Ref	0.07 (− 0.07, 0.20)	0.337	0.08 (−0.06, 0.22)	0.259	0.07 (− 0.07, 0.21)	0.325	0.02 (− 0.04, 0.08)	0.541
Paraben
MeP	Ref	−0.14 (− 0.27, − 0.01)	0.044	− 0.14 (− 0.28, 0.01)	0.060	− 0.14 (− 0.30, 0.02)	0.078	−0.05 (− 0.13, 0.02)	0.155
PrP	Ref	−0.01 (− 0.15, 0.12)	0.829	− 0.06 (− 0.20, 0.08)	0.406	−0.10 (− 0.26, 0.05)	0.189	−0.03 (− 0.09, 0.03)	0.394
Pesticides
2,5-DCP	Ref	0.05 (−0.09, 0.19)	0.465	0.16 (0.02, 0.30)	0.023	0.09 (−0.05, 0.24)	0.214	0.03 (−0.03, 0.08)	0.327
2,4-DCP	Ref	−0.05 (− 0.19, 0.10)	0.514	0.06 (− 0.09, 0.21)	0.401	− 0.05 (− 0.20, 0.11)	0.568	−0.02 (− 0.10, 0.06)	0.611
Phthalate metabolites
MBzP	Ref	0.05 (−0.09, 0.18)	0.519	−0.03 (− 0.18, 0.11)	0.653	− 0.02 (− 0.18, 0.14)	0.826	−0.01 (− 0.12, 0.10)	0.862
MEP	Ref	0.02 (−0.12, 0.16)	0.773	0.12 (−0.03, 0.27)	0.108	0.14 (−0.02, 0.30)	0.083	0.12 (0.02, 0.21)	0.017
MiBP	Ref	0.14 (−0.01, 0.28)	0.054	0.07 (−0.08, 0.22)	0.376	0.10 (−0.07, 0.27)	0.251	0.05 (−0.08, 0.18)	0.471

NHANES National Health and Nutrition Examination Survey, CI Confidence interval; Total means continuous chemical variable. Multivariable linear regression was conducted and regression coefficients (β) were calculated while comparing the second, third and fourth quartiles of each chemical with reference to the first exposure quartile (N = 2372). Models were adjusted for age, gender, race, educational levels, family income-to-poverty ratio, caloric intake, serum cotinine, and log-transformed creatinine

ISSN: 1476-069X