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Table 5 Association between the WQS index and obesity in NHANES 2005–2010 (N = 2372)

From: Using three statistical methods to analyze the association between exposure to 9 compounds and obesity in children and adolescents: NHANES 2005-2010

Outcomes OR/ β 95% CI of OR P value
Obesity
 Model 1 1.50 (1.19, 1.90) < 0.001
 Model 2 1.51 (1.19, 1.91) < 0.001
 Model 3 1.48 (1.16, 1.89) 0.002
BMI z-score
 Model 1 0.028 (−0.09, 0.15) 0.643
 Model 2 0.033 (−0.09, 0.15) 0.584
 Model 3 0.001 (−0.12, 0.12) 0.983
  1. NHANES National Health and Nutrition Examination Survey, CI Confidence interval. The weighted quantile sum (WQS) regression was fitted for the obesity and BMI z-score, which scored all the chemical exposures into quantiles and estimated the weight index. OR estimates represent the odds ratios of obesity as 1 quartile increased in the WQS index. β estimates represent the mean differences in the BMI z-score as 1 quartile increased in the WQS index. Model 1: Adjusted for age, gender, ethnicity, and log-transformed creatinine. Model 2: Adjusted for age, gender, ethnicity, caloric intake, serum cotinine, and log-transformed creatinine. Model 3: Adjusted for age, gender, ethnicity, educational levels, family income-to-poverty ratio, caloric intake, serum cotinine, and log-transformed creatinine