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Table 5 Adjusted logistic regression coefficients and 95% confidence intervals for the associations between tertiles of PFAS (ng/mL) and PBDE (ng/g lipid) concentrations > 80% detection in maternal serum and preterm birth (N = 506)

From: Associations between prenatal maternal exposure to per- and polyfluoroalkyl substances (PFAS) and polybrominated diphenyl ethers (PBDEs) and birth outcomes among pregnant women in San Francisco

 

N (PTB, FTB)

OR

95% CI

PFAS

 PFOA

   < 1.40

(11, 155)

Reference

  1.40–0.96

(14, 151)

1.79

(0.75, 4.28)

   > 0.96

(16, 146)

2.37

(0.88, 6.38)

 PFOS

   < 1.40

(13, 153)

Reference

  1.40–2.56

(13, 155)

1.21

(0.50, 2.91)

   > 2.56

(15, 144)

1.87

(0.72, 4.88)

 PFHxS

   < 0.24

(13, 148)

Reference

  0.24–0.49

(17, 157)

1.32

(0.58, 3.02)

   > 0.49

(11, 147)

1.15

(0.38, 3.41)

 PFNA

   < 0.24

(12, 159)

Reference

  0.24–0.49

(24, 220)

1.88

(0.83, 4.30)

   > 0.49

(9, 82)

2.06

(0.72, 5.89)

 Me-PFOSA-AcOH

   < 0.04

(13, 152)

Reference

  0.04–0.06

(15, 156)

0.96

(0.40, 2.28)

   > 0.06

(18, 152)

1.14

(0.49, 2.63)

 Total PFAS

   < 2.62

(12, 157)

Reference

  2.62–4.83

(17, 154)

1.70

(0.70, 4.17)

   > 4.83

(16, 150)

2.08

(0.74, 5.82)

PBDE

 BDE-47

   < 8.47

(9, 157)

Reference

  8.47–14.22

(11, 158)

1.20

(0.47, 3.06)

   > 14.22

(21, 137)

2.35

(0.97, 5.72)

 BDE-99

   < 2.88

(13, 156)

Reference

  2.88–4.71

(11, 159)

0.78

(0.33, 1.88)

   > 4.71

(21, 146)

1.25

(0.55, 2.84)

 Total PBDE

   < 11.38

(10, 161)

Reference

  11.38–18.99

(13, 157)

1.21

(0.50, 2.95)

   > 18.99

(22, 143)

1.88

(0.79, 4.48)

  1. Abbreviations: PFAS per- and polyfluoroalkyl substances, PBDE polybrominated diphenyl ethers, OR odds ratio, CI confidence interval
  2. Models adjusted for maternal age, maternal race/ethnicity, pre-pregnancy BMI, maternal education, smoking status, parity, and food insecurity
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Environmental Health

ISSN: 1476-069X