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Table 1 Characteristics of the study population (n = 15,786), stratified by gender

From: Perfluoroalkyl substances are associated with elevated blood pressure and hypertension in highly exposed young adults

Variables Total (n = 15,786) Males (n = 7667) Females (n = 8119)
mean (SD) min-max Median (Q1-Q3) mean (SD) min-max Median (Q1-Q3) mean (SD) min-max Median (Q1-Q3)
PFAS
 PFOA (ng/mL) 59.69 (72.26) 0.35–1400 35.8 (13.7–78.9) 83.84 (87.51) 0.35–1400 58.3 (25.1–114.7) 36.89 (43.03) 0.35–671 22.6 (8.8–49.4)
 PFOS (ng/mL) 4.63 (4.02) 0.35–142 3.7 (2.5–5.6) 5.72 (4.43) 0.35–142 4.8 (3.3–6.9) 3.59 (3.27) 0.35–124 3 (2–4.4)
 PFHxS (ng/mL) 5.97 (6.82) 0.35–127 3.6 (1.6–7.8) 8.86 (8.29) 0.35–127 6.5 (3–12) 3.24 (3.19) 0.35–41.3 2.2 (1.1–4.3)
 PFNA (ng/mL) 0.53 (0.42) 0.35–39.7 0.35 (0.35–0.6) 0.59 (0.52) 0.35–39.7 0.5 (0.35–0.7) 0.48 (0.28) 0.35–8.8 0.35 (0.35–0.5)
Covariates
 Age (years) 30.04 (5.86) 20–39 30 (25–35) 29.88 (5.88) 20–39 30 (25–35) 30.2 (5.84) 20–39 31 (25–35)
 BMI (kg/m2) 23.91 (4.3) 13.58–50.47 23.27 (20.9–26.04) 24.75 (3.82) 13.58–49.01 24.22 (22.23–26.59) 23.11 (4.56) 14.32–50.47 22.04 (19.92–25.08)
 Time-lag (months) 14.77 (5.45) 3–28 14 (10–19) 14.7 (5.51) 5–28 14 (10–19) 14.84 (5.39) 3–28 14 (10–19)
Gender n (%)       
 Male 7667 (48.57)       
 Female 8119 (51.43)       
Education n (%) n (%) n (%)
 Elementary/Middle school 2409 (15.26) 1346 (17.56) 1063 (13.09)
 Highschool 9445 (59.83) 4847 (63.22) 4598 (56.63)
 University 3932 (24.91) 1474 (19.23) 2458 (30.27)
Physical activity n (%) n (%) n (%)
 Light 10,638 (67.39) 4719 (61.55) 5919 (72.9)
 Moderate 2394 (15.17) 1152 (15.03) 1242 (15.3)
 Heavy 2754 (17.45) 1796 (23.43) 958 (11.8)
Smoke n (%) n (%) n (%)
 NO 9230 (58.47) 3895 (50.8) 5335 (65.71)
 YES 4355 (27.59) 2575 (33.59) 1780 (21.92)
 Ex 2201 (13.94) 1197 (15.61) 1004 (12.37)
Country of birth n (%) n (%) n (%)
 HDC 14,297 (90.57) 7136 (93.07) 7161 (88.2)
 HMPC 1489 (9.43) 531 (6.93) 958 (11.8)
Outcomes
  n (%) n (%) n (%)
Hypertension 1971 (12.49) 1449 (18.9) 522 (6.43)
  Total (n= 15,380) Males (n= 7428) Females (n= 7952)
Blood pressure mean (SD) min-max Median (Q1-Q3) mean (SD) min-max Median (Q1-Q3) mean (SD) min-max Median (Q1-Q3)
Systolic BP (mmHg) 119.77 (14.23) 70–180 120 (110–130) 125.08 (13.51) 70–180 125 (118–134) 114.8 (13.04) 70–180 115 (105–122)
Diastolic BP (mmHg) 74.36 (9.74) 25–119 75 (70–80) 76.36 (9.58) 25–119 79 (70–81) 72.51 (9.51) 40–112 72 (65–80)
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