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Table 1 Characteristics of the study population (n = 15,786), stratified by gender

From: Perfluoroalkyl substances are associated with elevated blood pressure and hypertension in highly exposed young adults

Variables

Total (n = 15,786)

Males (n = 7667)

Females (n = 8119)

mean (SD)

min-max

Median (Q1-Q3)

mean (SD)

min-max

Median (Q1-Q3)

mean (SD)

min-max

Median (Q1-Q3)

PFAS

 PFOA (ng/mL)

59.69 (72.26)

0.35–1400

35.8 (13.7–78.9)

83.84 (87.51)

0.35–1400

58.3 (25.1–114.7)

36.89 (43.03)

0.35–671

22.6 (8.8–49.4)

 PFOS (ng/mL)

4.63 (4.02)

0.35–142

3.7 (2.5–5.6)

5.72 (4.43)

0.35–142

4.8 (3.3–6.9)

3.59 (3.27)

0.35–124

3 (2–4.4)

 PFHxS (ng/mL)

5.97 (6.82)

0.35–127

3.6 (1.6–7.8)

8.86 (8.29)

0.35–127

6.5 (3–12)

3.24 (3.19)

0.35–41.3

2.2 (1.1–4.3)

 PFNA (ng/mL)

0.53 (0.42)

0.35–39.7

0.35 (0.35–0.6)

0.59 (0.52)

0.35–39.7

0.5 (0.35–0.7)

0.48 (0.28)

0.35–8.8

0.35 (0.35–0.5)

Covariates

 Age (years)

30.04 (5.86)

20–39

30 (25–35)

29.88 (5.88)

20–39

30 (25–35)

30.2 (5.84)

20–39

31 (25–35)

 BMI (kg/m2)

23.91 (4.3)

13.58–50.47

23.27 (20.9–26.04)

24.75 (3.82)

13.58–49.01

24.22 (22.23–26.59)

23.11 (4.56)

14.32–50.47

22.04 (19.92–25.08)

 Time-lag (months)

14.77 (5.45)

3–28

14 (10–19)

14.7 (5.51)

5–28

14 (10–19)

14.84 (5.39)

3–28

14 (10–19)

Gender

n (%)

      

 Male

7667 (48.57)

      

 Female

8119 (51.43)

      

Education

n (%)

n (%)

n (%)

 Elementary/Middle school

2409 (15.26)

1346 (17.56)

1063 (13.09)

 Highschool

9445 (59.83)

4847 (63.22)

4598 (56.63)

 University

3932 (24.91)

1474 (19.23)

2458 (30.27)

Physical activity

n (%)

n (%)

n (%)

 Light

10,638 (67.39)

4719 (61.55)

5919 (72.9)

 Moderate

2394 (15.17)

1152 (15.03)

1242 (15.3)

 Heavy

2754 (17.45)

1796 (23.43)

958 (11.8)

Smoke

n (%)

n (%)

n (%)

 NO

9230 (58.47)

3895 (50.8)

5335 (65.71)

 YES

4355 (27.59)

2575 (33.59)

1780 (21.92)

 Ex

2201 (13.94)

1197 (15.61)

1004 (12.37)

Country of birth

n (%)

n (%)

n (%)

 HDC

14,297 (90.57)

7136 (93.07)

7161 (88.2)

 HMPC

1489 (9.43)

531 (6.93)

958 (11.8)

Outcomes

 

n (%)

n (%)

n (%)

Hypertension

1971 (12.49)

1449 (18.9)

522 (6.43)

 

Total (n = 15,380)

Males (n = 7428)

Females (n = 7952)

Blood pressure

mean (SD)

min-max

Median (Q1-Q3)

mean (SD)

min-max

Median (Q1-Q3)

mean (SD)

min-max

Median (Q1-Q3)

Systolic BP (mmHg)

119.77 (14.23)

70–180

120 (110–130)

125.08 (13.51)

70–180

125 (118–134)

114.8 (13.04)

70–180

115 (105–122)

Diastolic BP (mmHg)

74.36 (9.74)

25–119

75 (70–80)

76.36 (9.58)

25–119

79 (70–81)

72.51 (9.51)

40–112

72 (65–80)