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Table 1 F3 generation pesticides lineage males pathology. The individual animals for the pesticides lineage males are listed and a (+) indicates presence of disease and (−) absence of disease. The shaded disease identifies those animals used for that disease molecular analysis. The number of animals with disease versus total number of animals and percentage is presented. The comparison no disease animals are indicated with a (0)

From: Epigenome-wide association study for pesticide (Permethrin and DEET) induced DNA methylation epimutation biomarkers for specific transgenerational disease

Molecular ID

Late Puberty

Testis

Prostate

Kidney

Obesity

Tumor

Multiple Disease

Total Disease

PS1

–

–

–

–

–

–

–

0

PS2

–

–

–

–

–

–

–

0

PS3

–

+

–

–

–

–

–

1

PS4

–

+

–

–

–

–

–

1

PS5

–

–

–

–

–

–

–

0

PS6

–

–

–

–

–

–

–

0

PS7

–

–

–

–

–

–

–

0

PS8

–

–

–

–

–

–

–

0

PS9

–

+

–

–

–

–

–

1

PS10

–

–

–

–

–

–

–

0

PS11

–

–

–

–

–

–

–

0

PS12

–

–

–

–

–

–

–

0

PS13

–

–

–

–

–

–

–

0

PS14

–

+

–

+

–

–

+

2

PS15

–

–

–

–

–

–

–

0

PS16

–

–

–

+

–

–

–

1

PS17

–

n/a

+

–

–

–

–

1

PS18

–

–

–

–

–

–

–

0

PS19

–

–

+

–

–

–

–

1

PS20

–

+

+

+

+

–

+

4

PS21

–

–

–

–

–

–

–

0

PS22

–

+

+

–

–

–

+

2

PS23

–

–

–

+

–

–

–

1

PS24

–

–

–

–

–

–

–

0

PS25

–

–

–

+

–

–

–

1

PS26

–

–

+

–

–

–

–

1

PS27

+

+

–

+

+

–

+

4

PS28

–

–

–

+

–

–

–

1

PS29

–

+

–

–

+

–

+

2

PS30

–

+

–

+

–

–

+

2

PS31

–

–

–

+

–

–

–

1

PS32

+

+

–

–

–

–

+

2

PS33

+

–

–

–

–

–

–

1

PS34

+

–

–

+

–

–

+

2

PS35

n/a

+

+

–

–

–

+

2

PS36

n/a

+

–

+

–

–

+

2

PS37

n/a

+

+

+

–

–

+

3

PS38

n/a

+

–

+

–

–

+

2

PS39

–

–

–

–

–

+

–

1

PS40

–

–

+

–

–

–

–

1

PS41

–

–

–

+

–

–

–

1

Totals

4/37 = 11%

14/40 = 35%

8/41 = 20%

14/41 = 34%

3/41 = 7%

1/41 = 2%

12/41 = 29%

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