TY - JOUR AU - Preston, Emma V. AU - Eberle, Claudia AU - Brown, Florence M. AU - James-Todd, Tamarra PY - 2020 DA - 2020/11/09 TI - Climate factors and gestational diabetes mellitus risk – a systematic review JO - Environmental Health SP - 112 VL - 19 IS - 1 AB - Current and projected increases in global temperatures and extreme climate events have led to heightened interest in the impact of climate factors (i.e. ambient temperature, season/seasonality, and humidity) on human health. There is growing evidence that climate factors may impact metabolic function, including insulin sensitivity. Gestational diabetes mellitus (GDM) is a common pregnancy complication, with an estimated global prevalence of up to 14%. While lifestyle and genetic risk factors for GDM are well established, environmental factors may also contribute to GDM risk. Previous reviews have summarized the growing evidence of environmental risk factors for GDM including endocrine disrupting chemicals and ambient air pollution. However, studies of the effects of climate factors on GDM risk have not been systematically evaluated. Therefore, we conducted a systematic review to summarize and evaluate the current literature on the associations of climate factors with GDM risk. SN - 1476-069X UR - https://doi.org/10.1186/s12940-020-00668-w DO - 10.1186/s12940-020-00668-w ID - Preston2020 ER -