Fig. 1From: The effects of everyday-life exposure to polycyclic aromatic hydrocarbons on biological age indicatorsConceptual hierarchical framework and summary of steps in the analysis. The latent variable “exposure to PAH” was considered as the distal determinant a), acting through the proximate determinant b) “anti-B[a]PDE–DNA” (intermediate variable or mechanism) to affect the final outcomes c) “tl50” (LTL median) or, alternatively, LmtDNAcnBack to article page