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Table 3 Relative changes in FeNO per log-transformed IQR increase in BC at different lag periods

From: Exposure to traffic-related air pollution and changes in exhaled nitric oxide and DNA methylation in arginase and nitric oxide synthase in children with asthma

Lag Model 1 p Model 2 p Model 3 p Model 4 p
n Relative change in FeNO (95%CI)   n Relative change in FeNO (95%CI)   n Relative change in FeNO (95%CI)   n Relative change in FeNO (95%CI)  
Lag 0-6 h 89 1.14 (1.03, 1.26) 0.01 89 1.14 (1.02, 1.27) 0.02 89 1.14 (1.03, 1.28) 0.02 73 1.17 (1.02, 1.33) 0.02
Lag 7-12 h 89 1.12 (1.00, 1.25) 0.06 89 1.12 (0.99, 1.26) 0.07 89 1.12 (0.99, 1.26) 0.07 73 1.21 (1.05, 1.38) 0.01
Lag 13-24 h 89 0.97 (0.88, 1.07) 0.55 89 0.97 (0.88, 1.07) 0.55 89 0.97 (0.88, 1.07) 0.54 73 0.99 (0.89, 1.11) 0.91
Lag 0-24 h 89 1.03 (0.95, 1.13) 0.45 89 1.03 (0.94, 1.13) 0.52 89 1.03 (0.94, 1.13) 0.53 73 1.04 (0.93, 1.15) 0.49
Lag 25-48 h 86 0.96 (0.87, 1.07) 0.47 86 0.96 (0.86, 1.07) 0.49 86 0.96 (0.86, 1.07) 0.47 70 0.98 (0.86, 1.12) 0.75
Lag 49-72 h 83 1.11 (1.00, 1.24) 0.06 83 1.11 (0.98, 1.26) 0.09 83 1.11 (0.98, 1.26) 0.09 67 1.06 (0.92, 1.21) 0.44
Lag 73-96 h 80 1.12 (1.00, 1.25) 0.06 80 1.12 (0.99, 1.26) 0.07 80 1.12 (0.99, 1.26) 0.07 64 1.07 (0.94, 1.22) 0.32
  1. Note: All estimates are from linear mixed effect model to reflect percent changes in FeNO per IQR increase in log-transformed BC. The IQR (μg/m3) was 1.8 for lag 0-6 h, 1.8 for lag 7-12 h, 1.2 for lag 13-24 h, 1.1 for lag 0-24 h, 1.5 for lag 25-48 h, 1.6 for lag 49-72 h and 1.3 for lag 73-96 h
  2. Model 1 was the unadjusted model
  3. Model 2 adjusted for day-of-week and week number when FeNO data were collected
  4. Model 3 further adjusted for age, gender and race/ethnicity
  5. Model 4 further adjusted for NO2