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Table 3 Numbers of observed and expected deaths, SMRs, and 95% CI for major causes of death in male Japanese Yusho patients in 10-year intervals, 1968 to 2017

From: Mortality in Yusho patients exposed to polychlorinated biphenyls and polychlorinated dibenzofurans: a 50-year retrospective cohort study

Cause of death (ICD–9 codes) Number of years since the accident
0–9 (1968–1977) 10–19 (1978–1987) 20–29 (1988–1997) 30–39 (1998–2007) 40–49 (2008–2017)
Obs, no. Exp, no. SMR 95% CI Obs, no. Exp, no. SMR 95% CI Obs, no. Exp, no. SMR 95% CI Obs, no. Exp, no. SMR 95% CI Obs, no. Exp, no. SMR 95% CI
All causes (001–999) 43 32.3 1.33 0.96, 1.79 73 58.8 1.24 0.97, 1.56 72 70.4 1.02 0.80, 1.29 86 86.7 0.99 0.79, 1.23 86 99.9 0.86 0.69, 1.06
All cancers (140–208) 16 6.4 2.48 1.42, 4.03 27 16.0 1.69 1.11, 2.46 25 23.2 1.08 0.70, 1.59 37 30.0 1.23 0.87, 1.70 27 32.5 0.83 0.55, 1.21
 Stomach (151) 9 2.7 3.35 1.53, 6.35 3 4.8 0.62 0.13, 1.82 5 5.0 1.01 0.33, 2.35 4 5.2 0.76 0.21, 1.95 3 4.8 0.62 0.13, 1.82
 Rectum (154) 0 0.2 0.00 0.00, 14.80 0 0.7 0.00 0.00, 5.60 2 1.0 2.03 0.25, 7.32 0 1.3 0.00 0.00, 2.90 2 1.4 1.46 0.18, 5.27
 Liver (155) 3 0.6 5.18 1.07, 15.15 5 2.0 2.55 0.83, 5.96 6 3.4 1.78 0.65, 3.87 3 3.7 0.81 0.17, 2.37 2 3.0 0.66 0.08, 2.38
 Pancreas (157) 0 0.3 0.00 0.00, 14.17 2 0.8 2.41 0.29, 8.69 1 1.3 0.76 0.02, 4.24 3 1.8 1.68 0.35, 4.91 2 2.3 0.88 0.11, 3.18
 Lung (162) 2 0.8 2.55 0.31, 9.21 9 2.8 3.23 1.48, 6.14 5 4.9 1.03 0.33, 2.39 12 6.9 1.74 0.90, 3.03 9 7.9 1.14 0.52, 2.17
 Breast (174) 0 0.0     0 0.0     0 0.0     0 0.0     0 0.0    
 Uterus (179–182)                          
 Leukemia (204–208) 0 0.2 0.00 0.00, 17.05 2 0.4 4.94 0.60, 17.85 0 0.5 0.00 0.00, 7.37 0 0.6 0.00 0.00, 5.96 0 0.7 0.00 0.00, 5.17
Diabetes mellitus (250) 1 0.4 2.85 0.07, 15.90 0 0.6 0.00 0.00, 5.74 0 0.9 0.00 0.00, 4.13 0 1.1 0.00 0.00, 3.43 0 1.1 0.00 0.00, 3.28
Hypertension (401–405) 0 0.7 0.00 0.00, 5.60 1 0.8 1.22 0.03, 6.82 0 0.5 0.00 0.00, 8.08 1 0.3 2.95 0.07, 16.45 0 0.4 0.00 0.00, 9.13
Heart disease (393–398, 410–429) 7 4.0 1.76 0.71, 3.63 10 9.9 1.01 0.48, 1.85 10 11.4 0.88 0.42, 1.62 11 12.3 0.90 0.45, 1.61 16 14.2 1.13 0.65, 1.84
Cerebrovascular disease (430–438) 7 7.6 0.92 0.37, 1.89 10 10.8 0.92 0.44, 1.70 9 9.3 0.97 0.44, 1.84 8 10.2 0.78 0.34, 1.54 5 9.1 0.55 0.18, 1.28
Hepatic disease (570–573) 2 1.1 1.74 0.21, 6.30 4 2.2 1.80 0.49, 4.60 4 2.0 2.05 0.56, 5.25 1 1.6 0.61 0.02, 3.40 1 1.5 0.66 0.02, 3.69
  1. Abbreviation: Exp Expected, ICD–9 International Classification of Diseases, Ninth Revision, Obs Observed, SMR Standardized mortality ratio, CI Confidence interval
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