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Table 2 Alterations in CD284 (TLR4) and CD14 in human neutrophils. Neutrophils were treated for 2 h without or with BPA (16 nM or 1.6 μM) or LPS (10 μg/ml)

From: Sex-dependent dysregulation of human neutrophil responses by bisphenol A

  CD284 (TLR4) CD14
% of positive cells MFI % of positive cells MFI
Women
mean ± SD [%]
Men
mean ± SD [%]
Women
mean ± SD
Men
mean ± SD
Women
mean ± SD [%]
Men
mean ± SD [%]
Women
mean ± SD
Men
mean ± SD
PMN 6.27 ± 2.03 6.14 ± 1.99 4.26 ± 3.22 3.87 ± 4.02 52.15 ± 13.2 54.6 ± 14.58 65.64 ± 19.29 68.01 ± 7.98
PMN + LPS 32.8b ± 8.41 28.3b ± 8.09 25.93 ± 4.88 24.75b ± 5.74 84.7b ± 17.12 92.8b ± 18.07 121.54 ± 25.22 135.22 ± 32.22
PMN + BPA
(16 nM)
16.3a ± 4.29 15.33a ± 4.99 9.43 ± 3.33 8.48 ± 2.22 78.1a ± 16.03 79.2a ± 16.65 91.23 ± 10.11 93.82 ± 21.91
PMN + BPA
(1.6 μM)
24.75a ± 7.99 22.7a ± 6.13 18.77 ± 6.55 15.43 ± 8.77 59.6 ± 18.01 55.1 ± 15.64 72.22 ± 24.22 69.11 ± 13.22
PMN + E2
(100 pM)
7.95 ± 1.97 6.2 ± 1.78 5.11 ± 4.21 3.99 ± 0.98 58.12 ± 19.22 60.6 ± 21.3 71.22 ± 32.22 74.38 ± 17.77
  1. Value significantly different between: acells without and with BPA (p < 0.05), bcells incubated only with LPS and cells incubated without BPA and LPS (p < 0.05). MFI mean fluorescence intensity