Table 2 Alterations in CD284 (TLR4) and CD14 in human neutrophils. Neutrophils were treated for 2 h without or with BPA (16 nM or 1.6 μM) or LPS (10 μg/ml)
From: Sex-dependent dysregulation of human neutrophil responses by bisphenol A
CD284 (TLR4) | CD14 | |||||||
|---|---|---|---|---|---|---|---|---|
% of positive cells | MFI | % of positive cells | MFI | |||||
Women mean ± SD [%] | Men mean ± SD [%] | Women mean ± SD | Men mean ± SD | Women mean ± SD [%] | Men mean ± SD [%] | Women mean ± SD | Men mean ± SD | |
PMN | 6.27 ± 2.03 | 6.14 ± 1.99 | 4.26 ± 3.22 | 3.87 ± 4.02 | 52.15 ± 13.2 | 54.6 ± 14.58 | 65.64 ± 19.29 | 68.01 ± 7.98 |
PMN + LPS | 32.8b ± 8.41 | 28.3b ± 8.09 | 25.93 ± 4.88 | 24.75b ± 5.74 | 84.7b ± 17.12 | 92.8b ± 18.07 | 121.54 ± 25.22 | 135.22 ± 32.22 |
PMN + BPA (16 nM) | 16.3a ± 4.29 | 15.33a ± 4.99 | 9.43 ± 3.33 | 8.48 ± 2.22 | 78.1a ± 16.03 | 79.2a ± 16.65 | 91.23 ± 10.11 | 93.82 ± 21.91 |
PMN + BPA (1.6 μM) | 24.75a ± 7.99 | 22.7a ± 6.13 | 18.77 ± 6.55 | 15.43 ± 8.77 | 59.6 ± 18.01 | 55.1 ± 15.64 | 72.22 ± 24.22 | 69.11 ± 13.22 |
PMN + E2 (100 pM) | 7.95 ± 1.97 | 6.2 ± 1.78 | 5.11 ± 4.21 | 3.99 ± 0.98 | 58.12 ± 19.22 | 60.6 ± 21.3 | 71.22 ± 32.22 | 74.38 ± 17.77 |