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Table 4 Summary of the effect of BPA or E2 on neutrophil functions

From: Sex-dependent dysregulation of human neutrophil responses by bisphenol A

Function Test Tested substance
BPA (16 nM) BPA (1.6 μM) E2 (100 pM)
Women Men Women Men Women Men
Chemotaxis Boyden chamber
Phagocytosis Park’s method with latex (%)
Phagocytosis Park’s method with latex (SCORE)
NADPH oxidase activity Park’s test with NBT/NBT spontaneous
NADPH oxidase activity Park’s test with NBT/NBT stimulated
NETs Fluorescence microscopy
CD284 (TLR4) Flow cytometry
CD14 Flow cytometry
NO Griess reaction
  1. Legend: ↑—increase, ↓—decrease, ↔—no statistical change. Abbreviations: BPA bisphenol A, E2 17β-estradiol, NETs neutrophil extracellular traps, NO nitric oxide, NBT nitroblue tetrazolium, SCORE Social Cohesion and Reconciliation