Skip to main content

Table 2 Least-square means of baseline lipids and apolipoproteins in total plasma according to tertile of PFASa

From: Associations of Perfluoroalkyl substances with blood lipids and Apolipoproteins in lipoprotein subspecies: the POUNDS-lost study

 

Total Cholesterol

Triglycerides

ApoB

ApoE

ApoC-III

PFOS (ng/ml)

 T1 (< 18.8)

180.9 ± 8.0

126.8 ± 11.6

86.6 ± 5.4

7.9 ± 0.4

13.7 ± 0.9

 T2 (18.8–33.1)

189.3 ± 7.9

132.4 ± 11.4

90.3 ± 5.3

8.2 ± 0.4

15.2 ± 0.9

 T3 (> 33.1)

190.7 ± 7.3

126.1 ± 10.5

94.0 ± 4.9

8.4 ± 0.4

14.8 ± 0.8

 P trend

0.21

0.80

0.11

0.22

0.36

PFOA (ng/ml)

 T1 (< 3.7)

189.1 ± 7.9

111.1 ± 11.2

85.7 ± 5.3

7.9 ± 0.4

13.4 ± 0.9

 T2 (3.7–5.6)

189.3 ± 7.6

137.3 ± 10.8

91.2 ± 5.0

8.2 ± 0.4

14.7 ± 0.9

 T3 (> 5.6)

188.4 ± 7.7

131.8 ± 10.9

95.4 ± 5.1

8.4 ± 0.4

15.5 ± 0.9

 P trend

0.67

0.06

0.03

0.12

0.007

PFHxS (ng/ml)

 T1 (< 1.8)

181.6 ± 7.8

119.4 ± 11.2

90.7 ± 5.2

8.4 ± 0.4

13.9 ± 0.9

 T2 (1.8–3.1)

189.3 ± 7.6

133.6 ± 11.0

89.7 ± 5.1

8.2 ± 0.4

14.9 ± 0.9

 T3 (> 3.1)

192.5 ± 7.8

130.8 ± 11.2

93.0 ± 5.2

8.1 ± 0.4

15.0 ± 0.9

 P trend

0.15

0.37

0.55

0.39

0.28

PFNA (ng/ml)

 T1 (< 1.1)

185.6 ± 7.7

132.9 ± 11.1

87.6 ± 5.2

7.9 ± 0.4

14.4 ± 0.9

 T2 (1.1–1.8)

186.1 ± 7.8

128.2 ± 11.2

89.8 ± 5.2

8.2 ± 0.4

14.4 ± 0.9

 T3 (> 1.8)

190.8 ± 7.5

123.6 ± 10.8

95.0 ± 5.0

8.4 ± 0.4

15.0 ± 0.9

 P trend

0.39

0.35

0.08

0.20

0.38

PFDA (ng/ml)

 T1 (< 0.3)

183.1 ± 7.9

138.9 ± 11.3

89.0 ± 5.3

7.9 ± 0.4

14.5 ± 0.9

 T2 (0.3–0.5)

186.6 ± 7.5

119.7 ± 10.7

88.2 ± 5.0

8.1 ± 0.4

14.3 ± 0.9

 T3 (> 0.5)

192.1 ± 7.6

129.3 ± 10.8

95.6 ± 5.0

8.5 ± 0.4

15.0 ± 0.9

 P trend

0.17

0.32

0.13

0.12

0.52

  1. Data are least squares (LS) means ± standard error (SE). aValues were adjusted for age (years), sex (men, women), race (White, non-White), educational attainment (high school or less, some college, and college graduate or beyond), smoking status (never, former, and current smoker), alcohol consumption (drinks/week), physical activity (MET-hr/wk), BMI (kg/m2), regular lipid-lowering medication use (yes or no), and dietary intervention groups (categorical)