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Table 4 Multiple logistic regression analysis of the association between osmolality adjusted maternal BPA exposure divided into tertiles and as continuous ln-transformed and the odds ratio (OR) and 95% confidence intervals (CI 95%) of an ASD-score ≥ 75th percentile compared to < 75th percentile (reference) in boys and girls at 2 and 5 years of age

From: Prenatal exposure to bisphenol A and autistic- and ADHD-related symptoms in children aged 2 and5 years from the Odense Child Cohort

Osmolality adjusted BPA (ng/ml)

All (N = 38/376)

Adjusteda OR (CI 95%)

Boys (N = 25/197)

Adjusteda OR (CI 95%)

Girls (N = 13/179)

Adjusteda OR (CI 95%)

ASD-score ≥ 75th percentile at both 2 and 5 years

 1th tertile (≤0.87)

Reference

Reference

Reference

 2nd tertile (0.88–1.96)

0.72 (0.26–2.01)

0.58 (0.15–2.17)

0.95 (0.17–5.52)

 3rd tertile (≥ 1.97)

2.05 (0.90–4.64)

2.17 (0.79–6.01)

1.94 (0.44–8.57)

 p-trendb

0.06

0.09

0.33

 Continuous lnBPA c

1.38 (1.02–1.84)*

1.42 (0.99–2.02)

1.34 (0.79–2.25)

  1. aAnalyses adjusted for maternal education, maternal age, pre-pregnancy BMI, child age at evaluation, parity. The sex-combined analyses were additionally adjusted for child sex
  2. bTrend across tertiles tested by inserting the tertile osmolality adjusted BPA as an ordinal indicator variable (0,1,2)
  3. cBPA inserted as a continuous variable transformed by the natural logarithm
  4. * P-value < 0.05
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Environmental Health

ISSN: 1476-069X