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Table 2 Children’s exposure to B[a]P exposure quartile categories and prevalence of asthma outcome (coded as dichotomous outcome (A) and nominal outcome (B)), stratified by the atopy- and gender-status of the children. Categorical variables are tested using Chi-square test of linear-by-linear association

From: Airborne Benzo[a]Pyrene may contribute to divergent Pheno-Endotypes in children

    Non-atopic Children   Atopic Children  
(A)    Controls Asthmatics   controls Asthmatics  
    N (%) N (%) P-value N (%) N (%) P-value
  B[a]P (ng/m3) Exposure Quartile Categories  
Boys < 2.3   22 (35%) 2 (10%) <0.001 1 (13%) 17 (31%) 0.068
2.3 - 4.2   11 (18%) 5 (25%) 7 (88%) 21 (38%)  
4.3 - 8.5   26 (41%) 0 (0%) 0 (0%) 6 (11%)  
≥ 8.6   4 (6%) 13 (65%) 0 (0%) 11 (20%)  
Total   63 (100%) 20 (100%) 8 (100%) 55 (100%)  
Girls < 2.3   11 (19%) 1 (6%) <0.001 3 (50%) 14 (41%) 0.066
2.3 - 4.2   18 (31%) 0 (0%) 3 (50%) 4 (12%)  
4.3 - 8.5   23 (40%) 0 (0%) 0 (0%) 2 (6%)  
≥ 8.6   6 (10%) 16 (94%) 0 (0%) 14 (41%)  
Total   58 (100%) 17 (100%) 6 (100%) 34 (100%)  
(B)   Lean Control OV/OB Control Lean Asthma OV/OB asthma   Lean Control OV/OB Control Lean Asthma OV/OB asthma  
   N (%) N (%) N (%) N (%)   N (%) N (%) N (%) N (%)  
  B[a]P (ng/m3) Exposure Quartile Categories
Boys < 2.3 19 (34%) 3 (43%) 0 (0%) 2 (67%) 0.020 1 (14%) 0 (0%) 15 (35%) 2 (17%) 0.258
2.3 - 4.2 8 (14%) 3 (43%) 4 (24%) 1 (33%) 6 (86%) 1 (100%) 15 (35%) 6 (50%)  
4.3 - 8.5 25 (45%) 1 (14%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 5 (12%) 1 (8%)  
≥ 8.6 4 (7%) 0 (0%) 13 (77%) 0 (0%) 0 (0%) 0 (0%) 8 (19%) 3 (25%)  
Total 56 (100%) 7 (100%) 17 (100%) 3 (100%) 7 (100%) 1 (100%) 43 (100%) 12 (100%)  
Girls < 2.3 10 (18%) 1 (33%) 1 (9%) 0 (0%) <0.001 3 (60%) 0 (0%) 12 (52%) 2 (18%) 0.013
2.3 - 4.2 17 (31%)   1 (33%) 0 (0%) 0 (0%) 2 (40%) 1 (100%) 3 (13%) 1 (9%)  
4.3 - 8.5 22 (40%)   1 (33%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 1 (4%) 1 (9%)  
≥ 8.6 6 (11%)   0 (0%) 10 (91%) 6 (100%) 0 (0%) 0 (0%) 7 (30%) 7 (64%)  
Total 55 (100%   3 (100%) 11 (100%) 6 (100%) 5 (100%) 1 (100%) 23 (100%) 11 (100%)