Table 2 Children’s exposure to B[a]P exposure quartile categories and prevalence of asthma outcome (coded as dichotomous outcome (A) and nominal outcome (B)), stratified by the atopy- and gender-status of the children. Categorical variables are tested using Chi-square test of linear-by-linear association
From: Airborne Benzo[a]Pyrene may contribute to divergent Pheno-Endotypes in children
Non-atopic Children | Atopic Children | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
(A) | Controls | Asthmatics | controls | Asthmatics | ||||||||||||||||
N | (%) | N | (%) | P-value | N | (%) | N | (%) | P-value | |||||||||||
B[a]P (ng/m3) Exposure Quartile Categories | ||||||||||||||||||||
Boys | < 2.3 | 22 | (35%) | 2 | (10%) | <0.001 | 1 | (13%) | 17 | (31%) | 0.068 | |||||||||
2.3 - 4.2 | 11 | (18%) | 5 | (25%) | 7 | (88%) | 21 | (38%) | ||||||||||||
4.3 - 8.5 | 26 | (41%) | 0 | (0%) | 0 | (0%) | 6 | (11%) | ||||||||||||
≥ 8.6 | 4 | (6%) | 13 | (65%) | 0 | (0%) | 11 | (20%) | ||||||||||||
Total | 63 | (100%) | 20 | (100%) | 8 | (100%) | 55 | (100%) | ||||||||||||
Girls | < 2.3 | 11 | (19%) | 1 | (6%) | <0.001 | 3 | (50%) | 14 | (41%) | 0.066 | |||||||||
2.3 - 4.2 | 18 | (31%) | 0 | (0%) | 3 | (50%) | 4 | (12%) | ||||||||||||
4.3 - 8.5 | 23 | (40%) | 0 | (0%) | 0 | (0%) | 2 | (6%) | ||||||||||||
≥ 8.6 | 6 | (10%) | 16 | (94%) | 0 | (0%) | 14 | (41%) | ||||||||||||
Total | 58 | (100%) | 17 | (100%) | 6 | (100%) | 34 | (100%) | ||||||||||||
(B) | Lean Control | OV/OB Control | Lean Asthma | OV/OB asthma | Lean Control | OV/OB Control | Lean Asthma | OV/OB asthma | ||||||||||||
N | (%) | N | (%) | N | (%) | N | (%) | N | (%) | N | (%) | N | (%) | N | (%) | |||||
B[a]P (ng/m3) Exposure Quartile Categories | ||||||||||||||||||||
Boys | < 2.3 | 19 | (34%) | 3 | (43%) | 0 | (0%) | 2 | (67%) | 0.020 | 1 | (14%) | 0 | (0%) | 15 | (35%) | 2 | (17%) | 0.258 | |
2.3 - 4.2 | 8 | (14%) | 3 | (43%) | 4 | (24%) | 1 | (33%) | 6 | (86%) | 1 | (100%) | 15 | (35%) | 6 | (50%) | ||||
4.3 - 8.5 | 25 | (45%) | 1 | (14%) | 0 | (0%) | 0 | (0%) | 0 | (0%) | 0 | (0%) | 5 | (12%) | 1 | (8%) | ||||
≥ 8.6 | 4 | (7%) | 0 | (0%) | 13 | (77%) | 0 | (0%) | 0 | (0%) | 0 | (0%) | 8 | (19%) | 3 | (25%) | ||||
Total | 56 | (100%) | 7 | (100%) | 17 | (100%) | 3 | (100%) | 7 | (100%) | 1 | (100%) | 43 | (100%) | 12 | (100%) | ||||
Girls | < 2.3 | 10 | (18%) | 1 | (33%) | 1 | (9%) | 0 | (0%) | <0.001 | 3 | (60%) | 0 | (0%) | 12 | (52%) | 2 | (18%) | 0.013 | |
2.3 - 4.2 | 17 | (31%) | 1 | (33%) | 0 | (0%) | 0 | (0%) | 2 | (40%) | 1 | (100%) | 3 | (13%) | 1 | (9%) | ||||
4.3 - 8.5 | 22 | (40%) | 1 | (33%) | 0 | (0%) | 0 | (0%) | 0 | (0%) | 0 | (0%) | 1 | (4%) | 1 | (9%) | ||||
≥ 8.6 | 6 | (11%) | 0 | (0%) | 10 | (91%) | 6 | (100%) | 0 | (0%) | 0 | (0%) | 7 | (30%) | 7 | (64%) | ||||
Total | 55 | (100% | 3 | (100%) | 11 | (100%) | 6 | (100%) | 5 | (100%) | 1 | (100%) | 23 | (100%) | 11 | (100%) | ||||