Skip to main content

Table 3. Adjusted odds of asthma (coded as either dichotomous outcome (A) or multinomial outcome (B)) per unit increase in exposure to natural-log transformed B[a]P and stratified according to atopy- and sex-

From: Airborne Benzo[a]Pyrene may contribute to divergent Pheno-Endotypes in children

  Main exposure Main Health Outcome groups of interest
   Non-atopic Children   Atopic Children
(A).   Control (Reference)    Asthmatics   Control (Reference)    Asthmatics
   N    N   N    N
OR (95% CI) OR (95% CI)   OR (95% CI) OR (95% CI)
P-value P-value   P-value P-value
Male one ln-unit B[a]P N = 63    N = 20   N = 8    N = 55
1 4.7 (1.9―11.5)   1 2.0 (0.4―11.1)
  P = 0.001    P = 0.331
Female one ln-unit B[a]P N = 58    N = 1   N = 6    N = 34
1 44.8 (4.7―428.2)   1 3.0 (0.7―12.7)
  P = 0.001    P = 0.173
(B).   Lean Control (Reference) OV/OB Control Lean Asthmatics OV/OB Asthmatics   Lean Control (reference) OV/OB Control Lean Asthmatics OV/OB Asthmatics
   N N N N   N N N N
OR (95% CI) OR (95% CI)c OR (95% CI) OR (95% CI)   OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
P-value P-value P-value P-value   P-value P-value P-value P-value
Male one ln-unit B[a]P N = 56 N = 7 N = 17 N = 3   N = 7 N = 1 N = 43 N = 12
1 0.3 (0.11.0) 9.6 (2.9―32.1) 0.3 (0.12.1)   1 0.4 (0.0173.1) 1.6 (0.39.7) 2.2 (0.314.9)
  P = 0.054 P < 0.001 P = 0.247    P = 0.786 P = 0.594 P = 0.409
Female one ln-unit B[a]P N = 55 N = 3 N = 11 N = 6   N = 5 N = 1 N = 23 N = 11
1 0.3 (0.02.9) 27.4 (3.2―237.1) 46.1 (1.7―1271.4)   1 0.0 (0.00.0) 3.6 (0.623.3) 17.1 (1.8―165.6)
  P = 0.286 P = 0.003 P = 0.024    P = 0.998 P = 0.173 P = 0.014
  1. The dichotomous outcome model adjusts for Creatinine adjusted Cotinine, (ln) 15-F-2t-IsoP, (ln) 8-oxodG, and lung function deficit. The models adjust for Cotinine, lung function deficit, 15-F2t-IsoP, and 8-oxodG