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Table 3 Associations between genotypes of acrylamide-metabolising enzymes and birth outcomes

From: Cord blood acrylamide levels and birth size, and interactions with genetic variants in acrylamide-metabolising genes

SNPa Estimated change in birth outcome (95% CI)
Birth weight (gram) p Birth length (cm) p Birth head circumference (CM) p
rs915906 24.5 (−36.9, 86.0) 0.43 −0.17 (− 0.44, 0.10) 0.22 − 0.04 (− 0.26, 0.19) 0.74
rs2480258 19.1 (−40.3, 78.5) 0.53 − 0.19 (− 0.45, 0.07) 0.16 − 0.02 (− 0.24, 0.20) 0.85
rs11101888 18.8 (− 56.0, 93.7) 0.62 0.05 (− 0.28, 0.38) 0.77 0.19 (− 0.07, 0.44) 0.15
rs1051740 −17.6 (−76.3, 41.1) 0.56 0.05 (− 0.21, 0.31) 0.70 − 0.02 (− 0.23, 0.20) 0.89
rs1695 2.0 (−56.2, 60.2) 0.95 −0.02 (− 0.28, 0.23) 0.86 0.04 (− 0.17, 0.25) 0.71
rs1138272 −7.3 (−86.6, 72.1) 0.86 −0.09 (− 0.44, 0.26) 0.60 − 0.03 (− 0.32, 0.27) 0.86
  1. Adjusted for: maternal pre-pregnancy BMI (kg/m2), maternal weight gain during pregnancy, maternal smoking during pregnancy (n cigarettes/day), parity (n children), gestational age (weeks), newborn’s sex and date of delivery
  2. amodeled is the regression coefficient of 1 or 2 variant alleles of the SNP compared to the homozygous wildtype