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Table 1 Association between exposure to traffic related air pollutants in pregnancy and wheezing development

From: The first 1000 days of life: traffic-related air pollution and development of wheezing and asthma in childhood. A systematic review of birth cohort studies

References

Type of study, country

Subjects, no

Pollutants and exposure assessment

Outcome

Positive association with the outcome

Sensitivity windows

Soh S et al., 2018 [10]

GUSTO birth cohort, Singapore

953

PM2.5

Daily exposure

Wheezing

(birth up to 2 years)

Yes

No sensitive trimester

Madsen C et al., 2017 [11]

MoBa, pregnancy cohort, Norway

17,533

NO2

Annual average estimates at residential address at birth

Wheezing

(6 to 18 months)

No

NA

Rosa MJ et al., 2017 [12]

PROGRESS pregnancy cohort, Mexico

552

PM2.5

Daily exposure

Wheezing

(birth up to 4 years)

No

No sensitive trimester

Aguilera I et al., 2013 [13]

Four birth cohorts of the INMA project, Spain

2199

NO2

Annual average estimates at residential address in pregnancy

Wheezing

(birth up to 12–18 months)

No

NA

  1. PM2.5 Particulate matter < 2.5 μm in diameter; NO2 Nitrogen dioxide, NA Not assessed