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Table 5 The results of subgroup analysis by types of BPR

From: Clinical outcomes associated with long-term exposure to airborne particulate pollution in kidney transplant recipients

 

TCMR

ABMR

Variables

HR

95% CI

P Value

HR

95% CI

P Value

Age at transplantation

0.998

0.989

2.739

0.6959

1.073

1.016

1.134

0.0117

Smoking

1.148

0.846

4.277

0.3769

3.067

0.535

17.590

0.2085

Body mass index

1

0.995

2.730

0.8204

0.986

0.843

1.154

0.8641

Hypertension

0.999

0.675

4.017

0.9963

0.624

0.102

3.803

0.6089

Diabetes mellitus

0.884

0.675

3.171

0.3698

0.569

0.142

2.282

0.4263

Sex (male)

1.152

0.929

3.922

0.1963

0.441

0.138

1.406

0.1661

HLA mismatch

1.219

1.147

3.596

<.0001

1.19

0.843

1.680

0.3219

Cause of ESRD (DM)

1.153

0.803

4.552

0.44

0.826

0.108

6.312

0.8539

Cause of ESRD (HTN)

1.065

0.652

4.738

0.8025

   

a

Cause of ESRD (GN)

0.945

0.745

3.263

0.6416

1.682

0.486

5.818

0.4116

Cause of ESRD (others)

1.032

0.706

4.104

0.8693

0.406

0.036

4.564

0.4652

Phosphorus

1.042

0.981

3.010

0.1828

0.995

0.686

1.442

0.9773

Albumin

0.906

0.791

2.835

0.1528

0.652

0.328

1.297

0.2231

eGFR at 6 months

0.989

0.982

2.707

0.0012

1.001

0.962

1.041

0.9796

preemptive

0.869

0.672

3.083

0.2849

1.062

0.329

3.432

0.9196

Annual mean PM10

1.053

1.043

2.895

<.0001

1.133

1.054

1.219

0.0008

Donor age

1.014

1.006

2.780

0.0009

0.998

0.953

1.044

0.9208

Donor sex

1.13

0.918

3.808

0.2491

2.051

0.604

6.957

0.2497

Donor type (Deceased)

1.348

1.057

4.913

0.0162

0.525

0.261

4.241

0.9435

ABO-incompatible

1.179

0.701

5.474

0.5346

5.89

1.184

29.297

0.0303

  1. Data are presented as mean and standard deviation unless otherwise indicated. Covariates are given as measured at the time of kidney transplantation. TCMR acute T-cell mediated rejection, ABMR acute antibody-mediated rejection, DCGF death-censored graft failure, HLA human leukocyte antigen, ESRD end stage renal disease, DM diabetes mellitus, HTN hypertension, GN glomerulonephritis, eGFR estimated glomerular filtration rate. The multivariable model was adjusted for age, smoking, BMI, hypertension, DM, sex, HLA mismatch, cause of ESRD, serum phosphorus, albumin, eGFR at 6 months, preemptive, annual mean PM10, donor age, sex, donor type, and ABO-incompatible
  2. ahese are unestimable due to the lack of the events