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Table 2 Risk ratios (95% confidence intervals) for associations between preterm birth and covariates among PROTECT participants in fully-adjusted modified Poisson modela

From: Preterm birth and PM2.5 in Puerto Rico: evidence from the PROTECT birth cohort

Covariate

RR (95% CI)

p-value

Individual-level covariates

 Infant sex

  Female

1.00 (Ref)

 

  Male

1.18 (0.77, 1.81)

0.460

 Mother’s age (years)

1.05 (1.00, 1.09)

0.035

 Number of pregnancies, including this one

  This one only

1.00 (Ref)

 

  Have had other pregnancies

0.74 (0.42, 1.29)

0.282

 Mother’s education

 

0.688

  College

1.00 (Ref)

 

  High school or technical school

1.26 (0.73, 2.20)

 

  Less than high school

1.38 (0.56, 3.38)

 

 Marital status at first study visit

  Married

1.00 (Ref)

 

  Single, divorced, or cohabiting

1.78 (1.14, 2.78)

0.012

 Employed at first study visit

  Yes

1.00 (Ref)

 

  No

1.66 (0.95, 2.89)

0.074

 Family income per year, US dollars

   < 30,000

1.00 (Ref)

 

   ≥ 30,000

0.93 (0.54, 1.58)

0.777

 Mother’s race

  Hispanic white

1.00 (Ref)

 

  Black or other race

1.28 (0.84, 1.95)

0.247

 History of adverse pregnancy outcomes

  No

1.00 (Ref)

 

  Yes

1.37 (0.79, 2.35)

0.258

 Any cigarette smoke exposure in the home

  No

1.00 (Ref)

 

  Yes

1.01 (0.61, 1.67)

0.984

 Alcohol consumption in past year, days per week

  0

1.00 (Ref)

 

  1 or more

0.70 (0.34, 1.45)

0.339

 Delivery type

  Vaginal

1.00 (Ref)

 

  Caesarian

1.55 (0.99, 2.43)

0.057

 Exercise habits

  Not exercise for > 30 min/day in past 3 months

1.00 (Ref)

 

  Exercised for > 30 min/day in past 3 months

0.94 (0.57, 1.57)

0.821

 Maternal pre-pregnancy BMI

 

0.059

  Normal or underweight

1.00 (Ref)

 

  Overweight

1.66 (1.02, 2.68)

 

  Obese

1.70 (1.00, 2.89)

 

Municipal-level covariates

 Household income, 2013 inflation-adjusted US dollars

  Below median for PR (USD 22,754)

1.00 (ref)

 

  Above median

1.00 (1.00, 1.00)

0.343

 Population density

   median for PR (2760/mile2)

1.00 (ref)

 

   > median

1.00 (1.00, 1.00)

0.159

 % adults (>  25 yr) with < high school education

   median for PR (23.9%)

1.00 (ref)

 

   > median

1.07 (1.00, 1.14)

0.052

 % occupied units with 1 or more severe housing problemsb

   median for PR (34.8%)

1.00 (ref)

 

   > Above median

0.99 (0.96, 1.03)

0.597

 % non-white, non-Hispanic population

   median for PR (35.7%)

1.00 (ref)

 

   > median

1.02 (0.99, 1.06)

0.252

 Average unemployment rate, 2004–2013

   median for PR (10.3%)

1.00 (ref)

 

   > median

1.07 (0.85, 1.35)

0.555

 Age adjusted diabetes prevalence, 2004–2013

   median for PR (12.4%)

1.00 (ref)

 

   > median

2.19 (1.00, 4.79)

0.051

  1. aAll models are adjusted for individual-level covariates (mother’s age, number of other children [alive or deceased], infant’s sex, gestational age, season of birth, education level, urban/rural residence, marital status, number of prenatal visits attended, and year of birth) and area/municipality-level covariates (including population density, income per capita, proportion of non-white non-Hispanic residents, average unemployment rate, proportion of occupied housing units with at least one of four severe US Department of Housing and Urban Development-designated defects, percentage of residents with a less than high school level of education, and the age adjusted prevalence of diabetes mellitus)
  2. bThese are designated by the US Department of Housing and Urban Development as overcrowding, lack of kitchen, lack of plumbing, and high housing cost