From: Occupational exposure to polycyclic aromatic hydrocarbons and risk of prostate cancer
Exposure | Prostate cancer | |||
---|---|---|---|---|
n Controls | n Cases | ORa | 95%CI | |
PAHs from any source | ||||
Never exposed | 1053 | 1009 | 1.00 | Ref |
Ever exposed | 573 | 560 | 1.00 | (0.85, 1.18) |
Duration (per 5-year increment) | 573 | 560 | 1.00 | (0.97, 1.03) |
Cumulative exposure | ||||
0.01—300.00 | 303 | 293 | 0.99 | (0.81, 1.20) |
300.01—1049.66 | 125 | 130 | 1.03 | (0.78, 1.37) |
> 1049.66 | 143 | 137 | 1.01 | (0.76, 1.33) |
p for trend | 0.93 | |||
Benzo[a]pyrene | ||||
Ever exposed | 188 | 182 | 1.00 | (0.78, 1.26) |
Duration (per 5-year increment) | 188 | 182 | 0.97 | (0.92, 1.03) |
Cumulative exposure | ||||
0.01—226.95 | 94 | 103 | 1.12 | (0.81, 1.55) |
226.96—588.00 | 42 | 42 | 1.03 | (0.64, 1.65) |
> 588.00 | 52 | 37 | 0.73 | (0.45, 1.20) |
p for trend | 0.25 | |||
PAHs from petroleum | ||||
Ever exposed | 516 | 514 | 1.01 | (0.85, 1.19) |
Duration (per 5-year increment) | 516 | 514 | 1.01 | (0.97, 1.04) |
Cumulative exposure | ||||
0.01—240.50 | 266 | 278 | 1.06 | (0.86, 1.30) |
240.51—901.00 | 120 | 115 | 0.89 | (0.67, 1.20) |
> 901.00 | 130 | 121 | 1.02 | (0.76, 1.37) |
p for trend | 0.93 | |||
PAHs from wood | ||||
Ever exposed | 42 | 50 | 1.24 | (0.79, 1.95) |
Duration (per 5-year increment) | 42 | 50 | 1.06 | (0.95, 1.18) |
Cumulative exposure | ||||
0.01—450.00 | 21 | 24 | 1.13 | (0.60, 2.16) |
450.01—1732.50 | 10 | 8 | 0.94 | (0.33, 2.66) |
> 1732.50 | 11 | 18 | 1.54 | (0.60, 3.92) |
p for trend | 0.32 | |||
PAHs from coal | ||||
Ever exposed | 57 | 57 | 0.97 | (0.66, 1.44) |
Duration (per 5-year increment) | 57 | 57 | 0.95 | (0.87, 1.04) |
Cumulative exposure | ||||
0.01—142.50 | 30 | 36 | 1.15 | (0.68, 1.95) |
142.51—546.25 | 12 | 14 | 1.18 | (0.52, 2.70) |
> 546.25 | 15 | 7 | 0.46 | (0.18, 1.17) |
p for trend | 0.12 | |||
PAHs from other sources | ||||
Ever exposed | 88 | 91 | 0.95 | (0.68, 1.31) |
Duration (per 5-year increment) | 88 | 91 | 1.01 | (0.94, 1.08) |
Cumulative exposure | ||||
0.01—200.00 | 44 | 41 | 0.89 | (0.56, 1.41) |
200.01—725.00 | 21 | 19 | 0.73 | (0.37, 1.42) |
> 725.00 | 23 | 31 | 1.19 | (0.62, 2.30) |
p for trend | 0.59 |