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Fig. 3 | Environmental Health

Fig. 3

From: Exposure to arsenic at different life-stages and DNA methylation meta-analysis in buccal cells and leukocytes

Fig. 3

Volcano and Manhattan plots of differentially variable positions (DVPs) and differentially variable regions (DVRs). A and B. Volcano plot and Manhattan plot of meta-analysis of PBMC EWAS (i.e., the Chile PBMC study, Bangladesh 450K study, and Bangladesh 850K study) adjusted for age, smoking status, cell type proportions, and sex (in the Chile studies). C and D. Volcano plot and Manhattan plot of meta-analysis of PBMC and buccal cell EWAS (i.e., the Chile PBMC study, Chile buccal cell study, Bangladesh 450K study, and Bangladesh 850K study) adjusted for age, smoking status, cell type proportions, and sex (in the Chile studies). In all plots, DVPs at FDR < 0.05 are shown as black points; the Bonferroni and FDR levels of significance are indicated by a solid and dashed red line, respectively; and DVRs are indicated by blue lines

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Environmental Health

ISSN: 1476-069X